Metallic Barium-Promoted Alkylation of Isatin Derivatives

The Barbier-type alkylation of isatin derivatives with alkyl halides, including benzylic halides, was achieved by using metallic barium as the promoter. The reaction is applicable to selected alkyl iodides and benzylic/prenylic bromides under metallic barium-promoted Barbier-type conditions.

Authors

Shun Haeno
Akira Yanagisawa (ORCID: https://orcid.org/0000-0003-4770-9087)

Institutions

Chiba University (JP)

Publication Details

Journal: Synlett
Published: 2026-06-29
DOI: https://doi.org/10.1055/a-2903-4456
Primary Topic: Coordination Chemistry and Organometallics
Type: article
Field-Weighted Citation Impact: 0.00

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article

Metallic Barium-Promoted Alkylation of Isatin Derivatives

Shun Haeno, Akira Yanagisawa

Jun 29, 2026

Synlett

Coordination Chemistry and Organometallics

article

Metallic Barium-Promoted Alkylation of Isatin Derivatives

Shun Haeno, Akira Yanagisawa

June 29, 2026article en

Abstract

Synlett

Chiba University (JP)

Openalex Percentile: Top 14%

Coordination Chemistry and Organometallics

DOI Source OpenAlex

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Metallic Barium-Promoted Alkylation of Isatin Derivatives — Shun Haeno, Akira Yanagisawa · Synlett (2026) | TGRS Research Map | TGRS