Virologic Outcomes After LA ART Initiation with and without Viremia in Two Large U.S. Clinic Cohorts

Long-acting cabotegravir/rilpivirine supports virologic suppression among people with HIV (PWH) facing adherence challenges. In two large U.S. cohorts(n=1,070), 96% of viremic PWH achieved virologic suppression at a 4-week median. However, blips/failure were more frequent among PWH initiating with viremia, underscoring the need for careful monitoring and optimization of long-acting treatment.

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Publication Details

Journal
Clinical Infectious Diseases
Published
2026-06-29
DOI
https://doi.org/10.1093/cid/ciag392
Primary Topic
HIV/AIDS Research and Interventions
Type
article
Field-Weighted Citation Impact
0.00
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article

Virologic Outcomes After LA ART Initiation with and without Viremia in Two Large U.S. Clinic Cohorts

Jonathan A. Colasanti, Matthew Spinelli, Chesa Cox, David V. Glidden et al.
Clinical Infectious Diseases
HIV/AIDS Research and Interventions
article

Virologic Outcomes After LA ART Initiation with and without Viremia in Two Large U.S. Clinic Cohorts

Jonathan A. Colasanti, Matthew Spinelli, Chesa Cox, David V. Glidden, Monica Gandhi, Megan J. Heise, Amalia Aldredge, Larisa Niles-Carnes, Eudiah Ochieng, Lauren Frances Collins, Nathanael Gistand, Meredith H. Lora, Jon Oskarsson, Janet Grochowski
article en

Abstract

Long-acting cabotegravir/rilpivirine supports virologic suppression among people with HIV (PWH) facing adherence challenges. In two large U.S. cohorts(n=1,070), 96% of viremic PWH achieved virologic suppression at a 4-week median. However, blips/failure were more frequent among PWH initiating with viremia, underscoring the need for careful monitoring and optimization of long-acting treatment.

Clinical Infectious Diseases
Grady Memorial Hospital (US), Emory University (US), University of California, San Francisco (US)
Good health and well-being
Openalex Percentile: Top 8%
HIV/AIDS Research and Interventions
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Virologic Outcomes After LA ART Initiation with and without Viremia in Two Large U.S. Clinic Cohorts — Jonathan A. Colasanti, Matthew Spinelli, et al. · Clinical Infectious Diseases (2026) | TGRS Research Map | TGRS