A window of opportunity: tear cytokine profiles in chronic ocular graft-versus-host disease
Chronic ocular graft-versus-host disease (GvHD) complicates allogeneic stem cell transplantation, with immune-mediated inflammation and fibrosis of the ocular surface leading to severe dry eye disease (DED). While previous studies have demonstrated elevated tear cytokines in chronic ocular GvHD, few have characterised early-stage cytokine correlations with clinical severity [ 1 , 2 , 3 ].
Authors
- Joan Ní Gabhann (ORCID: https://orcid.org/0000-0002-4247-3952)
- Conor C. Murphy (ORCID: https://orcid.org/0000-0003-2171-0418)
- E. Greenan
- E. Vandenberghe
- S. L. Annett
- F. O’Connell
- J. K. Dowling
- E. Conneally
- J. O’Sullivan
Institutions
- Royal College of Surgeons in Ireland (IE)
- Trinity College (CA)
- Trinity College Dublin (IE)
- Royal Victoria Eye and Ear Hospital (IE)
- Dublin Business School (IE)
- European Institute of Women's Health (IE)
- Health Research Board (IE)
- St. James's Hospital (IE)
- Future Analytics (IE)
Publication Details
- Journal
- Eye
- Published
- 2026-06-29
- DOI
- https://doi.org/10.1038/s41433-026-04674-z
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Irish Research eLibrary