Pure Laparoscopic Living Donor Right Hepatectomy: A Multifactorial Evolutional Learning Curve Analysis From a Single‐Surgeon High‐Volume Series

BACKGROUND: Pure laparoscopic donor right hepatectomy (PLDRH) is a safe technique, but its learning curve is often oversimplified. This study evaluates variables contributing to evolutional patterns for mastering PLDRH. METHODS: Consecutive donors undergoing PLDRH at a single center (2014-2021) were collected. A cumulative sum (CUSUM) method assessed a composite score derived from graft weight (GW), bile duct (BD) anatomy, operative time (OT), and warm ischemia time (WIT). Segmented regression identified the statistical breakpoint in the composite learning curve. RESULTS: Among 215 donors, no conversion occurred. Major post-operative complications (Clavien-Dindo ≥ 3) were reported in 2 (0.9%) cases with no mortality. CUSUM analysis identified a significant technical breakpoint at case 180 (p < 0.001). While OT and WIT improved after 60 cases (p < 0.001), surgical complexity, specifically GW and multiple BD, simultaneously increased between 60 and 180 cases. This demonstrates a multiphasic learning process where technical maturity was achieved by case 180, maintaining high safety standards despite progressive inclusion of larger grafts and more complex anatomy. CONCLUSION: The PLDRH learning curve is multifactorial and non-linear. While approximately 60 cases suffice for technical standardization, achieving full mastery over complex donors requires further caution. This multifactorial "evolutional" approach provides a comprehensive understanding for targeted improvement and surgical coaching.

Authors

Institutions

Publication Details

Journal
Journal of Hepato-Biliary-Pancreatic Sciences
Published
2026-06-29
DOI
https://doi.org/10.1002/jhbp.70152
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Pure Laparoscopic Living Donor Right Hepatectomy: A Multifactorial Evolutional Learning Curve Analysis From a Single‐Surgeon High‐Volume Series

Flavio Milana, Alessandro Parente, Sang Hoon Kim, Ki‐Hun Kim
Journal of Hepato-Biliary-Pancreatic Sciences
Hepatocellular Carcinoma Treatment and Prognosis
article

Pure Laparoscopic Living Donor Right Hepatectomy: A Multifactorial Evolutional Learning Curve Analysis From a Single‐Surgeon High‐Volume Series

Flavio Milana, Alessandro Parente, Sang Hoon Kim, Ki‐Hun Kim
article en

Abstract

BACKGROUND: Pure laparoscopic donor right hepatectomy (PLDRH) is a safe technique, but its learning curve is often oversimplified. This study evaluates variables contributing to evolutional patterns for mastering PLDRH. METHODS: Consecutive donors undergoing PLDRH at a single center (2014-2021) were collected. A cumulative sum (CUSUM) method assessed a composite score derived from graft weight (GW), bile duct (BD) anatomy, operative time (OT), and warm ischemia time (WIT). Segmented regression identified the statistical breakpoint in the composite learning curve. RESULTS: Among 215 donors, no conversion occurred. Major post-operative complications (Clavien-Dindo ≥ 3) were reported in 2 (0.9%) cases with no mortality. CUSUM analysis identified a significant technical breakpoint at case 180 (p < 0.001). While OT and WIT improved after 60 cases (p < 0.001), surgical complexity, specifically GW and multiple BD, simultaneously increased between 60 and 180 cases. This demonstrates a multiphasic learning process where technical maturity was achieved by case 180, maintaining high safety standards despite progressive inclusion of larger grafts and more complex anatomy. CONCLUSION: The PLDRH learning curve is multifactorial and non-linear. While approximately 60 cases suffice for technical standardization, achieving full mastery over complex donors requires further caution. This multifactorial "evolutional" approach provides a comprehensive understanding for targeted improvement and surgical coaching.

Journal of Hepato-Biliary-Pancreatic Sciences
King's College London (GB), Asan Medical Center (KR), University of Ulsan (KR), King's College Hospital NHS Foundation Trust (GB), IRCCS Humanitas Research Hospital (IT)
Quality Education
Openalex Percentile: Top 8%
Hepatocellular Carcinoma Treatment and Prognosis
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Pure Laparoscopic Living Donor Right Hepatectomy: A Multifactorial Evolutional Learning Curve Analysis From a Single‐Surgeon High‐Volume Series — Flavio Milana, Alessandro Parente, et al. · Journal of Hepato-Biliary-Pancreatic Sciences (2026) | TGRS Research Map | TGRS