Long‐Term Treatment With Juvéderm Hyaluronic Acid Injectables for ≥ 10 Years: Expert Considerations for Natural Outcomes

ABSTRACT Background Juvéderm is one of the most widely studied and broadly used hyaluronic acid (HA) product portfolios worldwide. Long‐term treatment can contribute greatly to positive aging, but clinical data over many cycles of injection are currently lacking. Following key principles of best practice can help to ensure natural outcomes are maintained over time. Aims To provide clinical expert considerations for long‐term and multiple treatments with Juvéderm, and present case studies treated for ≥ 10 years demonstrating effective and natural outcomes. Methods Six clinicians with various specialties and extensive experience with Juvéderm completed a written questionnaire. Their collective clinical expertise and experience form the basis of these considerations. Results Maintenance of natural results over long‐term Juvéderm treatment may be facilitated by: (i) strong technical fundamentals (e.g., optimized injection technique and in‐depth anatomical knowledge); (ii) correct product selection (e.g., understanding their composition, properties, preferred injection depths, and key clinical data); and (iii) long‐term planning (e.g., thorough patient assessment, consideration of the whole face, use of an initially conservative approach, combining Juvéderm products with other treatments in an individualized and multimodal strategy, and tracking appearance over time). Conclusions Following these key principles of best practice may help clinicians to achieve well‐tolerated and natural outcomes over long‐term treatment with Juvéderm HA injectables.