Acute PSP-like Syndrome Due to Paramedian Thalamopeduncular Infarction

We report a case of acute pseudo–progressive supranuclear palsy caused by a paramedian thalamopeduncular infarct. The patient presented with a sudden vertical gaze palsy, staring look, and postural instability, mimicking progressive supranuclear palsy. Magnetic resonance imaging showed an acute medial thalamic infarct extending into the midbrain, confirming a vascular etiology.

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Publication Details

Journal
Journal of Stroke Medicine
Published
2026-06-29
DOI
https://doi.org/10.1177/25166085261460101
Primary Topic
Ophthalmology and Eye Disorders
Type
article
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article

Acute PSP-like Syndrome Due to Paramedian Thalamopeduncular Infarction

Karthik Vinay Mahesh, Abeer Goel
Journal of Stroke Medicine
Ophthalmology and Eye Disorders
article

Acute PSP-like Syndrome Due to Paramedian Thalamopeduncular Infarction

Karthik Vinay Mahesh, Abeer Goel
article en

Abstract

We report a case of acute pseudo–progressive supranuclear palsy caused by a paramedian thalamopeduncular infarct. The patient presented with a sudden vertical gaze palsy, staring look, and postural instability, mimicking progressive supranuclear palsy. Magnetic resonance imaging showed an acute medial thalamic infarct extending into the midbrain, confirming a vascular etiology.

Journal of Stroke Medicine
Post Graduate Institute of Medical Education and Research (IN)
Good health and well-being
Openalex Percentile: Top 8%
Ophthalmology and Eye Disorders
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