TNF inhibitors for the long-term management of juvenile idiopathic arthritis associated uveitis: real-life data from the ITHACA cohort
OBJECTIVES: We assess prescription patterns and describe the long-term real-life effectiveness of different TNF inhibitors (TNFis) in juvenile idiopathic arthritis-related uveitis (JIA-U). METHODS: Patients with JIA-U treated with TNFi were retrospectively enrolled. RESULTS: < 0.01). CONCLUSIONS: All TNFis appear to be effective for long-term management of JIA-U. We observed some differences in the number of uveitis relapses and ocular complication rates favoring adalimumab over infliximab and etanercept, findings that need to be further confirmed in prospective studies.
Authors
- Cecilia Beatrice Chighizola (ORCID: https://orcid.org/0000-0002-3787-9632)
- Dariush Khaleghi Hashemian (ORCID: https://orcid.org/0000-0002-1881-231X)
- Valeria Edefonti (ORCID: https://orcid.org/0000-0002-1995-1477)
- M L Pandolfi
- Federico Rissotto (ORCID: https://orcid.org/0000-0002-1584-1801)
- Costanza Barresi (ORCID: https://orcid.org/0000-0003-4828-7170)
- Claudia Iannone (ORCID: https://orcid.org/0009-0005-5686-0127)
- C. Bochicchio
- Stefania Costi (ORCID: https://orcid.org/0000-0002-4468-6839)
- E Miserocchi
- Francesco Baldo
- Giovanna Lommano
- Achille Marino
- Federico Ambrogi
- Roberto Caporali
Institutions
- Vita-Salute San Raffaele University (IT)
- University of Milan (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- IRCCS Policlinico San Donato (IT)
- Istituto Ortopedico Gaetano Pini (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
Publication Details
- Journal
- Expert Opinion on Biological Therapy
- Published
- 2026-06-28
- DOI
- https://doi.org/10.1080/14712598.2026.2694688
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 0.00