A pair of epimeric lignan glycosides from <i>Selaginella tamariscina</i>

To explore the chemical constituents of Selaginella tamariscina and their effects on cancer cells, this study employed multiple chromatographic techniques including polyamide, silica gel, and semi-preparative High-performance liquid chromatography for compound isolation. The structures of the compounds were elucidated based on physicochemical properties and spectroscopic data. A pair of epimeric lignan glycosides, 7′R-tamariscinol U 4-O-β-d-glucopyranoside (1), 7′S-tamariscinol U 4-O-β-d-glucopyranoside (2) were obtained, along with two known compounds 3,5,7-trimethoxyflavone-4′-O-β-d-glucopyranoside (3) and selapeptin B (4). 1 and 2 are new, while the spectral data of 3 and 4 in methanol-d4 are reported for the first time.