Does early surgical intervention for type II dens fractures improve survival in octogenarians? A propensity-matched analysis

Study Design Retrospective Cohort Study.Objectives To compare mortality and downstream morbidity after early operative versus nonoperative management of isolated Type II dens fractures in octogenarians.Methods TriNetX was queried to identify patients aged 80 years and older with a new diagnosis of Type II dens fracture. Patients with spinal cord injury, traumatic brain injury, or other major traumatic injuries were excluded. Patients were stratified by early operative intervention, defined as surgical fixation within 14 days, versus nonoperative management, defined as no surgical fixation after diagnosis. The primary outcome was mortality. Propensity score matching was performed 1:1 using demographic and clinical variables. Mortality was assessed at 9 months, 1 year, 2 years, and 3 years. Secondary outcomes included hospital readmission and long-term post-injury opioid use between 6 months and 3 years.Results After matching, 156 patients were included in each cohort. No significant differences in mortality were observed between cohorts at 9 months, 1 year, 2 years, or 3 years. Early operative intervention was associated with lower 90-day readmission (7.1% vs 17.9%; OR 0.35, 95% CI 0.17–0.73; p = 0.0036), lower 6-month readmission (9.0% vs 21.2%; OR 0.37, 95% CI 0.19–0.72; p = 0.0026), and lower long-term post-injury opioid use (16.0% vs 26.9%; OR 0.52, 95% CI 0.30–0.90; p = 0.0191).Conclusions In octogenarians with isolated Type II dens fractures, early surgery was not associated with improved long-term mortality, but was associated with lower readmission and reduced long-term post-injury opioid use.

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Journal
British Journal of Neurosurgery
Published
2026-06-27
DOI
https://doi.org/10.1080/02688697.2026.2695383
Primary Topic
Spinal Fractures and Fixation Techniques
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article
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article

Does early surgical intervention for type II dens fractures improve survival in octogenarians? A propensity-matched analysis

Ziam Khan, Timothy Chryssikos, Kevin T. Kim, Parantap Patel
British Journal of Neurosurgery
Spinal Fractures and Fixation Techniques
article

Does early surgical intervention for type II dens fractures improve survival in octogenarians? A propensity-matched analysis

Ziam Khan, Timothy Chryssikos, Kevin T. Kim, Parantap Patel
article en

Abstract

Study Design Retrospective Cohort Study.Objectives To compare mortality and downstream morbidity after early operative versus nonoperative management of isolated Type II dens fractures in octogenarians.Methods TriNetX was queried to identify patients aged 80 years and older with a new diagnosis of Type II dens fracture. Patients with spinal cord injury, traumatic brain injury, or other major traumatic injuries were excluded. Patients were stratified by early operative intervention, defined as surgical fixation within 14 days, versus nonoperative management, defined as no surgical fixation after diagnosis. The primary outcome was mortality. Propensity score matching was performed 1:1 using demographic and clinical variables. Mortality was assessed at 9 months, 1 year, 2 years, and 3 years. Secondary outcomes included hospital readmission and long-term post-injury opioid use between 6 months and 3 years.Results After matching, 156 patients were included in each cohort. No significant differences in mortality were observed between cohorts at 9 months, 1 year, 2 years, or 3 years. Early operative intervention was associated with lower 90-day readmission (7.1% vs 17.9%; OR 0.35, 95% CI 0.17–0.73; p = 0.0036), lower 6-month readmission (9.0% vs 21.2%; OR 0.37, 95% CI 0.19–0.72; p = 0.0026), and lower long-term post-injury opioid use (16.0% vs 26.9%; OR 0.52, 95% CI 0.30–0.90; p = 0.0191).Conclusions In octogenarians with isolated Type II dens fractures, early surgery was not associated with improved long-term mortality, but was associated with lower readmission and reduced long-term post-injury opioid use.

British Journal of Neurosurgery
University of Maryland, Baltimore (US)
Good health and well-being
Openalex Percentile: Top 5%
Spinal Fractures and Fixation Techniques
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