Threshold dynamics of a time-delayed nonlocal reaction-diffusion cholera model with temporary immunity

In this paper, a nonlocal and time-delayed cholera model is formulated that incorporates temporary immunity of the hosts, and incubation periods in the hosts and pathogen. The basic reproduction number [Formula: see text] for the model system is derived. It is shown that this number gives the threshold dynamics: if [Formula: see text], there exists at least one positive steady state and that the disease persists; and if [Formula: see text], the disease will die out, provided that cholera have no impact on host mobility or the immunity for the host is permanent. For the special homogeneous case, an explicit formula of [Formula: see text] is obtained, and there is a unique globally attractive positive constant steady state as [Formula: see text]. Numerical simulations are illustrated to investigate the influence of diffusion coefficients and spatial heterogeneity on the spread of the disease, and explore the sensitivity of [Formula: see text] on the model parameters.

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Publication Details

Journal
International Journal of Biomathematics
Published
2026-06-26
DOI
https://doi.org/10.1142/s1793524526500695
Primary Topic
Mathematical and Theoretical Epidemiology and Ecology Models
Type
article
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article

Threshold dynamics of a time-delayed nonlocal reaction-diffusion cholera model with temporary immunity

Tailei Zhang, Junli Liu, Zhimin Li, Zhenghua Guo
International Journal of Biomathematics
Mathematical and Theoretical Epidemiology and Ecology Models
article

Threshold dynamics of a time-delayed nonlocal reaction-diffusion cholera model with temporary immunity

Tailei Zhang, Junli Liu, Zhimin Li, Zhenghua Guo
article en

Abstract

In this paper, a nonlocal and time-delayed cholera model is formulated that incorporates temporary immunity of the hosts, and incubation periods in the hosts and pathogen. The basic reproduction number [Formula: see text] for the model system is derived. It is shown that this number gives the threshold dynamics: if [Formula: see text], there exists at least one positive steady state and that the disease persists; and if [Formula: see text], the disease will die out, provided that cholera have no impact on host mobility or the immunity for the host is permanent. For the special homogeneous case, an explicit formula of [Formula: see text] is obtained, and there is a unique globally attractive positive constant steady state as [Formula: see text]. Numerical simulations are illustrated to investigate the influence of diffusion coefficients and spatial heterogeneity on the spread of the disease, and explore the sensitivity of [Formula: see text] on the model parameters.

International Journal of Biomathematics
Openalex Percentile: Top 6%
Mathematical and Theoretical Epidemiology and Ecology Models
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