Neuropsychological disorders in patients with serofast state

This study involved an analysis of neuropsychological functions in 68 patients, aged 27 to 64 years, who exhibited serofast state following syphilitic infection. A comprehensive approach was adopted, including questionnaires, neurological examinations, and cognitive assessments to evaluate participants' cognitive status. The primary objective of this research was to assess cognitive functioning among individuals in this population. The results indicated that a significant proportion of the subjects displayed a persistent craving for alcohol, suggesting potential dependence and alterations in their psycho-emotional state. Notably, among male participants, there was a higher incidence of aggressive behavior, difficulties in social adaptation, and a tendency toward spontaneous, unpredictable actions. Moreover, there was frequent disregard for generally accepted norms and behavioral standards. Conversely, female participants were more likely to exhibit abrupt mood fluctuations, which often resulted in conflictual behavior characterized by aggressive elements. Additionally, there were manifestations of vindictiveness and suspicion among the subjects. The inclination to manage emotional states through alcohol consumption was particularly evident among the women involved in the study.

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Publication Details

Journal
S S Korsakov Journal of Neurology and Psychiatry
Published
2026-06-26
DOI
https://doi.org/10.17116/jnevro202612606166
Primary Topic
Obsessive-Compulsive Spectrum Disorders
Type
article
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article

Neuropsychological disorders in patients with serofast state

U.S. Kostina, Владимир Викторович Шпрах, N.A. Shpakova
S S Korsakov Journal of Neurology and Psychiatry
Obsessive-Compulsive Spectrum Disorders
article

Neuropsychological disorders in patients with serofast state

U.S. Kostina, Владимир Викторович Шпрах, N.A. Shpakova
article en

Abstract

This study involved an analysis of neuropsychological functions in 68 patients, aged 27 to 64 years, who exhibited serofast state following syphilitic infection. A comprehensive approach was adopted, including questionnaires, neurological examinations, and cognitive assessments to evaluate participants' cognitive status. The primary objective of this research was to assess cognitive functioning among individuals in this population. The results indicated that a significant proportion of the subjects displayed a persistent craving for alcohol, suggesting potential dependence and alterations in their psycho-emotional state. Notably, among male participants, there was a higher incidence of aggressive behavior, difficulties in social adaptation, and a tendency toward spontaneous, unpredictable actions. Moreover, there was frequent disregard for generally accepted norms and behavioral standards. Conversely, female participants were more likely to exhibit abrupt mood fluctuations, which often resulted in conflictual behavior characterized by aggressive elements. Additionally, there were manifestations of vindictiveness and suspicion among the subjects. The inclination to manage emotional states through alcohol consumption was particularly evident among the women involved in the study.

S S Korsakov Journal of Neurology and PsychiatryVol. 126(6)
State Healthcare Institution "Regional Clinical Oncological Dispensary" (RU), Irkutsk State Medical University (RU)
Gender equality
Openalex Percentile: Top 5%
Obsessive-Compulsive Spectrum Disorders
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