Features and Clinical Significance of C-X-C Chemokine Receptor Type 4 Expression in Breast Cancer: A Prospective, Single-center Cohort Study

es, 2,3 neurogenesis, 4 germ cell development, cardiogenesis and angiogenesis, 5-7 and osteogenesis. 8In malignancies, CXCR4 is involved in tumor cell (TC) proliferation, metastasis, angiogenesis, and immune evasion. 1 CXCR4 expression can be activated in breast cancer (BC) cells after exposure to hypoxia, vascular endothelial growth factor, nuclear factor kappa B, estrogens, transforming growth factor β1, β-catenin, and interferon γ. [9][10][11][12] The interaction of CXCR4

Authors

Publication Details

Journal
Nature Cell and Science
Published
2026-06-26
DOI
https://doi.org/10.61474/ncs.2026.00013
Primary Topic
Chemokine receptors and signaling
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Features and Clinical Significance of C-X-C Chemokine Receptor Type 4 Expression in Breast Cancer: A Prospective, Single-center Cohort Study

M. A. Senchukova, Natalia Saidler
Nature Cell and Science
Chemokine receptors and signaling
article

Features and Clinical Significance of C-X-C Chemokine Receptor Type 4 Expression in Breast Cancer: A Prospective, Single-center Cohort Study

M. A. Senchukova, Natalia Saidler
article en

Abstract

es, 2,3 neurogenesis, 4 germ cell development, cardiogenesis and angiogenesis, 5-7 and osteogenesis. 8In malignancies, CXCR4 is involved in tumor cell (TC) proliferation, metastasis, angiogenesis, and immune evasion. 1 CXCR4 expression can be activated in breast cancer (BC) cells after exposure to hypoxia, vascular endothelial growth factor, nuclear factor kappa B, estrogens, transforming growth factor β1, β-catenin, and interferon γ. [9][10][11][12] The interaction of CXCR4

Nature Cell and ScienceVol. 4(2)
Good health and well-being
Openalex Percentile: Top 8%
Chemokine receptors and signaling
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Features and Clinical Significance of C-X-C Chemokine Receptor Type 4 Expression in Breast Cancer: A Prospective, Single-center Cohort Study — M. A. Senchukova, Natalia Saidler · Nature Cell and Science (2026) | TGRS Research Map | TGRS