Hybrid deep learning for mental workload classification using EEG with enhanced preprocessing and interpretability

Mental workload classification is critical in safety-sensitive fields such as healthcare and aviation. However, electroencephalography-based approaches still face challenges with generalizability, noise robustness, and interpretability. In this study, we propose an integrated hybrid deep learning framework to address these limitations and enable robust, interpretable electroencephalography-based mental workload classification. The proposed approach uses a Variational Autoencoder to enhance noise reduction and feature extraction from band-wise topographical videos, a Convolutional Block Attention Module to adaptively focus on important spatial-channel Electroencephalogram features, and a Bidirectional Long Short-Term Memory network to capture complex temporal dependencies under leave-one-subject-out cross-validation. We conducted ablation studies to identify each architecture component's contribution and sensitivity analyses to determine the optimal parameters. The model achieved the highest overall accuracy among the baselines and reached an average accuracy of 83.9% across subjects for classifying four mental workload levels. Ablation studies confirmed the added value of all three architecture components for improving performance. Sensitivity analyses identified optimal parameters, including a 10-second window length that balances temporal context and specificity. For better interpretability and neurophysiological insight, we used Gradient-weighted Class Activation Mapping to visualize key frontal-parietal brain regions and frequency bands associated with workload dynamics. Future research could explore adaptive windowing strategies, multimodal data integration, cross-dataset benchmarking, and evaluation against transformer-based and graph neural network architectures under consistent subject-independent evaluation settings to further enhance model generalizability.

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Publication Details

Journal
PLoS ONE
Published
2026-06-26
DOI
https://doi.org/10.1371/journal.pone.0352882
Primary Topic
EEG and Brain-Computer Interfaces
Type
article
Field-Weighted Citation Impact
0.00

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article

Hybrid deep learning for mental workload classification using EEG with enhanced preprocessing and interpretability

Zhi Lin Chong, Osama Abdelrahman, Esraa Faisal Malik, Wei Lin Teoh et al.
PLoS ONE
EEG and Brain-Computer Interfaces
article

Hybrid deep learning for mental workload classification using EEG with enhanced preprocessing and interpretability

Zhi Lin Chong, Osama Abdelrahman, Esraa Faisal Malik, Wei Lin Teoh, XinYing Chew, Khaw Khai Wah
article en

Abstract

Mental workload classification is critical in safety-sensitive fields such as healthcare and aviation. However, electroencephalography-based approaches still face challenges with generalizability, noise robustness, and interpretability. In this study, we propose an integrated hybrid deep learning framework to address these limitations and enable robust, interpretable electroencephalography-based mental workload classification. The proposed approach uses a Variational Autoencoder to enhance noise reduction and feature extraction from band-wise topographical videos, a Convolutional Block Attention Module to adaptively focus on important spatial-channel Electroencephalogram features, and a Bidirectional Long Short-Term Memory network to capture complex temporal dependencies under leave-one-subject-out cross-validation. We conducted ablation studies to identify each architecture component's contribution and sensitivity analyses to determine the optimal parameters. The model achieved the highest overall accuracy among the baselines and reached an average accuracy of 83.9% across subjects for classifying four mental workload levels. Ablation studies confirmed the added value of all three architecture components for improving performance. Sensitivity analyses identified optimal parameters, including a 10-second window length that balances temporal context and specificity. For better interpretability and neurophysiological insight, we used Gradient-weighted Class Activation Mapping to visualize key frontal-parietal brain regions and frequency bands associated with workload dynamics. Future research could explore adaptive windowing strategies, multimodal data integration, cross-dataset benchmarking, and evaluation against transformer-based and graph neural network architectures under consistent subject-independent evaluation settings to further enhance model generalizability.

PLoS ONEVol. 21(6)
Monash University Malaysia (MY), Universiti Sains Malaysia (MY), United Arab Emirates University (AE), Universiti Tunku Abdul Rahman (MY)
Universiti Sains Malaysia
Openalex Percentile: Top 6%
EEG and Brain-Computer Interfaces
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