Cutting Edge: Motion-Tracking Brillouin Microscopy for Corneal Mechanical Evaluation
In Brief Motion-tracking Brillouin microscopy enables direct, depth-resolved, spatially precise assessment of corneal mechanics, revealing focal anterior weakening as the earliest signature of keratoconus. By accurately identifying subclinical disease, this custom-built research device offers a unique, mechanics-based approach to refractive screening, ectasia risk assessment, and early keratoconus detection.
Authors
- J. Bradley Randleman (ORCID: https://orcid.org/0000-0001-8475-136X)
- Bassel Hammoud (ORCID: https://orcid.org/0000-0002-3464-749X)
- Barbara A.L. Dutra
- Bianca N. Susanna
- Hongyuan Zhang
- Giuliano Scarcelli
Institutions
- Universidade de São Paulo (BR)
- Cleveland Clinic Lerner College of Medicine (US)
- Cleveland Eye Clinic (US)
- University of Maryland, College Park (US)
Publication Details
- Journal
- Cornea
- Published
- 2026-06-26
- DOI
- https://doi.org/10.1097/ico.0000000000004215
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Foundation for the National Institutes of Health