How deep is deep enough? The importance of the detection limits of the CML minimal residual disease gDNA assay
Scientific support from CRIETT center of University of Insubria (instrument code MIC05) is greatly acknowledged. We gratefully acknowledge the Consorzio InterUniversitario per le Biotecnologie (CIB). We gratefully acknowledge AIL Varese Como ODV (Associazione Italiana contro Leucemie, Linfomi e Mieloma, sezione di Varese e Como) for the collaboration.
Authors
- Annalisa Frattini (ORCID: https://orcid.org/0000-0002-1166-3091)
- Orietta Spinelli (ORCID: https://orcid.org/0000-0003-0374-1536)
- Giuseppe Montalbano (ORCID: https://orcid.org/0000-0002-8195-4986)
- Roberto Valli (ORCID: https://orcid.org/0000-0002-3209-8917)
- Lucy Costantino (ORCID: https://orcid.org/0000-0001-6732-8092)
- Giorgio Binelli (ORCID: https://orcid.org/0000-0003-0223-7805)
- Rolland Reinbold (ORCID: https://orcid.org/0000-0002-1977-6154)
- Vittoria Moretti (ORCID: https://orcid.org/0000-0003-1150-5568)
- Tamara Intermesoli (ORCID: https://orcid.org/0000-0001-8067-8257)
- Clara Belotti
- Giovanni Micheloni (ORCID: https://orcid.org/0000-0002-7666-5311)
- Francesco Acquati (ORCID: https://orcid.org/0000-0002-9537-400X)
- Giovanni Porta (ORCID: https://orcid.org/0000-0002-5351-4596)
- Martina Milani
- Chiara Francesca Longo
Institutions
- University of Insubria (IT)
- Ospedale Papa Giovanni XXIII (IT)
- Institute of Genetic and Biomedical Research (IT)
- Centro Diagnostico Italiano (IT)
- Institute of Biomedical Technologies (IT)
Publication Details
- Journal
- Cell Death Discovery
- Published
- 2026-06-26
- DOI
- https://doi.org/10.1038/s41420-026-03221-9
- Primary Topic
- Chronic Myeloid Leukemia Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Consorzio Interuniversitario Biotecnologie
- Università degli Studi dell'Insubria
- Associazione Italiana Contro le Leucemie - Linfomi e Mieloma