Ongoing multi-country outbreak of carbapenem-resistant Enterobacter hormaechei ST1344 carrying bla NDM-5 in the European Union/European Economic Area, March 2025 to April 2026
ST1344 among patients has been detected. In minimum spanning tree analysis of core genome-multilocus sequence-typing (cgMLST) profiles, isolates cluster with ≤ 4 allelic differences. The outbreak includes 57 cases (29 female/28 male; median age: 73 years), which occurred between March 2025 and April 2026. Many were hospitalised (n = 45), some with extensive prior medical treatment, and only three reported travel abroad. A cross-border investigation, including coordinated exposure questionnaires, has not yet identified a source.
Authors
- Marie Meo
- Joanna Lis-Tønder
- Annelot F. Schoffelen (ORCID: https://orcid.org/0000-0003-3447-2009)
- Sandra Witteveen (ORCID: https://orcid.org/0000-0001-9132-9028)
- Daan W. Notermans (ORCID: https://orcid.org/0000-0002-9494-0989)
- Soheila Javadi (ORCID: https://orcid.org/0000-0002-2615-5962)
- Anke Kohlenberg
- Vilhelm Müller (ORCID: https://orcid.org/0000-0002-4554-2124)
- Ørjan Samuelsen (ORCID: https://orcid.org/0000-0002-5525-2614)
- Lisa-Marie Höfken
- Lone Jannok Porsbo
- Silver Anthony Wolf (ORCID: https://orcid.org/0009-0004-8164-7216)
- Olov Svartström (ORCID: https://orcid.org/0000-0003-3100-5325)
- Núria Balanza (ORCID: https://orcid.org/0000-0002-3581-0383)
- Anette M. Hammerum (ORCID: https://orcid.org/0000-0001-9471-1601)
- Heidrun Kerschner (ORCID: https://orcid.org/0000-0002-9094-371X)
- Marius Linkevičius (ORCID: https://orcid.org/0000-0001-5760-2721)
- Erik Alm (ORCID: https://orcid.org/0000-0002-2903-607X)
- Mirco Sandfort (ORCID: https://orcid.org/0000-0001-7078-6537)
- Henrik Hasman (ORCID: https://orcid.org/0000-0001-6314-2709)
- Sabine C. de Greeff (ORCID: https://orcid.org/0000-0002-4009-4991)
- Amelie M. Friedsam (ORCID: https://orcid.org/0000-0002-3877-295X)
- Louise Roer (ORCID: https://orcid.org/0000-0001-6892-913X)
- Rainer Hartl (ORCID: https://orcid.org/0000-0002-9007-6089)
- Monique Perrin
- Sarah Andrea Roth
- Miriam Sare
- Martin Cormican (ORCID: https://orcid.org/0000-0002-8023-1882)
- Antoni P A Hendrickx
- Claus Østergaard
- Monica T Y Wong
- Anne-Sophie Lagneaux
- Sebastian Haller
- Christina Clarke
Institutions
- Statens Serum Institut (DK)
- University Hospital of North Norway (NO)
- Public Health Agency of Sweden (SE)
- European Union (BE)
- Norwegian Institute of Public Health (NO)
- Ollscoil na Gaillimhe – University of Galway (IE)
- Robert Koch Institute (DE)
- University Hospital Galway (IE)
- Niedersächsisches Landesgesundheitsamt (DE)
- National Institute for Public Health and the Environment (NL)
- CNR de la Résistance aux Antibiotiques (FR)
- COPE Galway (IE)
- Lillebaelt Hospital (DK)
- Laboratoire National de Santé (LU)
- European Centre for Disease Prevention and Control (SE)
- Ruhr University Bochum (DE)
Publication Details
- Journal
- Eurosurveillance
- Published
- 2026-06-25
- DOI
- https://doi.org/10.2807/1560-7917.es.2026.31.25.2600460
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00