Complete Molar Pregnancy With Hyperthyroidism, High-Output Heart Failure and Peptoniphilus Species Bacteremia: A Case Report

A complete molar pregnancy is a rare but dangerous complication of pregnancy. Early diagnosis is crucial due to the potential harmful consequences, especially if recognized late. Complications include the malignant potential, hyperthyroidism, possible preeclampsia, and ovarian cysts. Here, we report a case study in which a 47-year-old woman with no medical history presented with heart failure and a systemic infection. Upon further investigation, she was found to have significant hyperthyroidism due to thyroid stimulation from a very high human chorionic gonadotropin (hCG) level, in the presence of a molar pregnancy. Furthermore, she was found to have bacteremia with Peptoniphilus species, typically present in the vaginal flora. This germ has not been previously demonstrated as a pathogen in the context of a molar pregnancy.

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Publication Details

Journal
Cureus
Published
2026-06-25
DOI
https://doi.org/10.7759/cureus.111523
Primary Topic
Gestational Trophoblastic Disease Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Complete Molar Pregnancy With Hyperthyroidism, High-Output Heart Failure and Peptoniphilus Species Bacteremia: A Case Report

Pascale Abrams, Jolan Kint, Louise Mees
Cureus
Gestational Trophoblastic Disease Studies
article

Complete Molar Pregnancy With Hyperthyroidism, High-Output Heart Failure and Peptoniphilus Species Bacteremia: A Case Report

Pascale Abrams, Jolan Kint, Louise Mees
article en

Abstract

A complete molar pregnancy is a rare but dangerous complication of pregnancy. Early diagnosis is crucial due to the potential harmful consequences, especially if recognized late. Complications include the malignant potential, hyperthyroidism, possible preeclampsia, and ovarian cysts. Here, we report a case study in which a 47-year-old woman with no medical history presented with heart failure and a systemic infection. Upon further investigation, she was found to have significant hyperthyroidism due to thyroid stimulation from a very high human chorionic gonadotropin (hCG) level, in the presence of a molar pregnancy. Furthermore, she was found to have bacteremia with Peptoniphilus species, typically present in the vaginal flora. This germ has not been previously demonstrated as a pathogen in the context of a molar pregnancy.

Cureus
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Openalex Percentile: Top 6%
Gestational Trophoblastic Disease Studies
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