Short-term Patient-Reported Outcomes After Primary Anterior Cruciate Ligament Reconstruction With and Without Lateral Extra-articular Tenodesis: A Matched-Cohort Analysis From the Swedish Knee Ligament Registry

Background: Despite reduced graft failure rates reported in randomized controlled trials comparing anterior cruciate ligament reconstruction (ACL-R) with and without lateral extra-articular tenodesis (LET), the impact of LET on postoperative patient-reported outcomes (PROs) remains poorly defined. Purpose: To compare short-term PROs, as well as anterior cruciate ligament (ACL) revision rates and clinical failure rates (defined as Knee injury and Osteoarthritis Outcome Score [KOOS] Quality of Life [QoL] value <44) between patients undergoing primary ACL-R with and without concomitant LET. Study Design: Cohort study; Level of evidence, 3. Methods: Data were extracted from the Swedish Knee Ligament Registry for all patients undergoing primary ACL-R between January 1, 2005, and June 25, 2025. Patients who underwent ACL-R + LET were matched to patients who underwent ACL-R without LET using 1:4 matching based on age, sex, body mass index, graft type, time from injury to reconstruction, and concomitant meniscal and cartilage injury status. The primary outcomes were KOOS values at the 1- and 2-year follow-ups. Secondary outcomes included revision ACL-R and clinical failure within 1 and 2 years. Categorical variables were compared using Fisher exact or chi-square tests, continuous variables were compared using Fisher nonparametric permutation tests, and within-group KOOS changes were compared using Wilcoxon signed-rank tests. Adjusted 1- and 2-year KOOS Symptoms comparisons for baseline differences and outcomes were interpreted relative to published minimal clinically important difference thresholds. Results: After matching, the final cohort consisted of 870 patients: 174 in the ACL-R + LET group and 696 in the ACL-R group. There were no significant between-group differences in KOOS 4 (mean of the Symptoms, Pain, Sports and Recreation, and QoL subscales) scores at the 1-year (77.7 ± 15.2 for ACL-R + LET vs 78.8 ± 14.9 for ACL-R) or 2-year (79.9 ± 16.7 for ACL-R + LET vs 80.7 ± 13.4 for ACL-) follow-up ( P > .5). Both groups demonstrated significant within-group improvements in KOOS 4 scores from baseline through the 2-year follow-up (all P ≤ .002). ACL revision rates at 2 years were 2.3% and 2.4% in the ACL-R + LET and ACL-R groups, respectively. Rates of clinical failure at 2 years were similar between groups (25.5% for ACL-R + LET vs 25.6% for ACL-R; P > .99). Conclusion: In this matched-cohort registry study, the addition of LET to primary ACL-R did not demonstrate superior short-term PROs at 1 or 2 years postsurgery.

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Journal
The American Journal of Sports Medicine
Published
2026-06-25
DOI
https://doi.org/10.1177/03635465261456637
Primary Topic
Knee injuries and reconstruction techniques
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article
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article

Short-term Patient-Reported Outcomes After Primary Anterior Cruciate Ligament Reconstruction With and Without Lateral Extra-articular Tenodesis: A Matched-Cohort Analysis From the Swedish Knee Ligament Registry

V Musahl, Alexandra Horváth, James A. Pruneski, Balint Zsidai et al.
The American Journal of Sports Medicine
Knee injuries and reconstruction techniques
article

Short-term Patient-Reported Outcomes After Primary Anterior Cruciate Ligament Reconstruction With and Without Lateral Extra-articular Tenodesis: A Matched-Cohort Analysis From the Swedish Knee Ligament Registry

V Musahl, Alexandra Horváth, James A. Pruneski, Balint Zsidai, Felix Öttl, Kristian Heder Ternell, Riccardo Cristiani, Kristian Samuelsson, Eric Hamrin Senorski
article en

Abstract

Background: Despite reduced graft failure rates reported in randomized controlled trials comparing anterior cruciate ligament reconstruction (ACL-R) with and without lateral extra-articular tenodesis (LET), the impact of LET on postoperative patient-reported outcomes (PROs) remains poorly defined. Purpose: To compare short-term PROs, as well as anterior cruciate ligament (ACL) revision rates and clinical failure rates (defined as Knee injury and Osteoarthritis Outcome Score [KOOS] Quality of Life [QoL] value <44) between patients undergoing primary ACL-R with and without concomitant LET. Study Design: Cohort study; Level of evidence, 3. Methods: Data were extracted from the Swedish Knee Ligament Registry for all patients undergoing primary ACL-R between January 1, 2005, and June 25, 2025. Patients who underwent ACL-R + LET were matched to patients who underwent ACL-R without LET using 1:4 matching based on age, sex, body mass index, graft type, time from injury to reconstruction, and concomitant meniscal and cartilage injury status. The primary outcomes were KOOS values at the 1- and 2-year follow-ups. Secondary outcomes included revision ACL-R and clinical failure within 1 and 2 years. Categorical variables were compared using Fisher exact or chi-square tests, continuous variables were compared using Fisher nonparametric permutation tests, and within-group KOOS changes were compared using Wilcoxon signed-rank tests. Adjusted 1- and 2-year KOOS Symptoms comparisons for baseline differences and outcomes were interpreted relative to published minimal clinically important difference thresholds. Results: After matching, the final cohort consisted of 870 patients: 174 in the ACL-R + LET group and 696 in the ACL-R group. There were no significant between-group differences in KOOS 4 (mean of the Symptoms, Pain, Sports and Recreation, and QoL subscales) scores at the 1-year (77.7 ± 15.2 for ACL-R + LET vs 78.8 ± 14.9 for ACL-R) or 2-year (79.9 ± 16.7 for ACL-R + LET vs 80.7 ± 13.4 for ACL-) follow-up ( P > .5). Both groups demonstrated significant within-group improvements in KOOS 4 scores from baseline through the 2-year follow-up (all P ≤ .002). ACL revision rates at 2 years were 2.3% and 2.4% in the ACL-R + LET and ACL-R groups, respectively. Rates of clinical failure at 2 years were similar between groups (25.5% for ACL-R + LET vs 25.6% for ACL-R; P > .99). Conclusion: In this matched-cohort registry study, the addition of LET to primary ACL-R did not demonstrate superior short-term PROs at 1 or 2 years postsurgery.

The American Journal of Sports Medicine
Freddie Mac (United States) (US), Tripler Army Medical Center (US), Sahlgrenska University Hospital (SE), Karolinska Institutet (SE), Universitätsklinik Balgrist (CH), Skåne University Hospital (SE), University of Gothenburg (SE)
Good health and well-being
Openalex Percentile: Top 5%
Knee injuries and reconstruction techniques
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