Waugh’s Syndrome in Adulthood: A Case Report of a Rare Combination of Intestinal Malrotation and Ileocolic Intussusception

Intestinal malrotation is an uncommon congenital anomaly resulting from abnormal rotation and fixation of the midgut during embryologic development. Although typically diagnosed during infancy, presentation in adulthood is rare and frequently associated with nonspecific symptoms. Adult intussusception is also an unusual condition and is commonly related to an underlying pathological lead point. The coexistence of intestinal malrotation and intussusception, known as Waugh’s syndrome, is exceptionally rare in adults. We report the case of a 76-year-old male presenting with intermittent abdominal pain, increased bowel frequency, and weight loss over two weeks. Physical examination revealed a palpable abdominal mass. Abdominal ultrasonography and contrast-enhanced computed tomography demonstrated ileocolic intussusception associated with intestinal malrotation. Exploratory laparotomy confirmed the diagnosis, revealing abnormal positioning of the bowel and an unreducible ileocolic intussusception. The patient underwent right colectomy with en bloc mesocolic resection and ileocolic anastomosis. Histopathological examination identified an inflammatory fibroid polyp as the lead point. Postoperative recovery was uneventful. Although rare, the association of intestinal malrotation and adult intussusception should be considered in patients presenting with bowel obstruction and atypical abdominal symptoms. Early recognition and surgical treatment are essential to achieve favorable outcomes.

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Publication Details

Journal
Cureus
Published
2026-06-26
DOI
https://doi.org/10.7759/cureus.111533
Primary Topic
Gastrointestinal disorders and treatments
Type
article
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article

Waugh’s Syndrome in Adulthood: A Case Report of a Rare Combination of Intestinal Malrotation and Ileocolic Intussusception

Ricardo Lemos, Francisco Sampaio, Barbara Freire, Laura Santos et al.
Cureus
Gastrointestinal disorders and treatments
article

Waugh’s Syndrome in Adulthood: A Case Report of a Rare Combination of Intestinal Malrotation and Ileocolic Intussusception

Ricardo Lemos, Francisco Sampaio, Barbara Freire, Laura Santos, Maria Moreira
article en

Abstract

Intestinal malrotation is an uncommon congenital anomaly resulting from abnormal rotation and fixation of the midgut during embryologic development. Although typically diagnosed during infancy, presentation in adulthood is rare and frequently associated with nonspecific symptoms. Adult intussusception is also an unusual condition and is commonly related to an underlying pathological lead point. The coexistence of intestinal malrotation and intussusception, known as Waugh’s syndrome, is exceptionally rare in adults. We report the case of a 76-year-old male presenting with intermittent abdominal pain, increased bowel frequency, and weight loss over two weeks. Physical examination revealed a palpable abdominal mass. Abdominal ultrasonography and contrast-enhanced computed tomography demonstrated ileocolic intussusception associated with intestinal malrotation. Exploratory laparotomy confirmed the diagnosis, revealing abnormal positioning of the bowel and an unreducible ileocolic intussusception. The patient underwent right colectomy with en bloc mesocolic resection and ileocolic anastomosis. Histopathological examination identified an inflammatory fibroid polyp as the lead point. Postoperative recovery was uneventful. Although rare, the association of intestinal malrotation and adult intussusception should be considered in patients presenting with bowel obstruction and atypical abdominal symptoms. Early recognition and surgical treatment are essential to achieve favorable outcomes.

Cureus
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Gastrointestinal disorders and treatments
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Waugh’s Syndrome in Adulthood: A Case Report of a Rare Combination of Intestinal Malrotation and Ileocolic Intussusception — Ricardo Lemos, Francisco Sampaio, et al. · Cureus (2026) | TGRS Research Map | TGRS