Do subjective and objective baseline sleep disturbances predict post-traumatic stress disorder treatment response? A secondary analysis of a randomized controlled trial

$\textbf{Background:}$ Sleep disturbances are highly prevalent in individuals with post-traumatic stress disorder (PTSD) and might interfere with trauma-focused treatments by disrupting memory consolidation, extinction and safety learning. However, evidence on the impact of sleep deficits on PTSD treatments remains inconclusive. $\textbf{Objective:}$ This study conducted a secondary analysis of a randomized controlled trial comparing cognitive processing therapy (CPT) and dialectical behaviour therapy for PTSD (DBT-PTSD) in women with PTSD. We examined whether subjective and objective baseline sleep disturbances predicted PTSD symptom reduction after up to 15 months of outpatient treatment, whether depression moderated this relationship, and whether effects differed for CPT and DBT-PTSD. $\textbf{Method:}$ Sleep was assessed in n = 178 women using actigraphy, sleep diaries, and the Pittsburgh sleep quality index (PSQI), applying linear mixed models for each sleep measure. $\textbf{Results:}$ Subjective sleep disturbances as measured in the PSQI did not significantly predict overall treatment outcomes for PTSD (p = .140). Additionally, depressive symptoms did not moderate this relationship (p = .469), and the effect did not differ for CPT and DBT-PTSD (p = .086). The same was found for sleep diary and actigraphy assessments. $\textbf{Conclusions:}$ These findings suggest that sleep disturbances do not hinder the effectiveness of long-term trauma-focused PTSD treatment in women with complex trauma presentations, implying that sleep-specific interventions may not be a prerequisite for initiating trauma-focused treatment in this population.

Authors

Publication Details

Journal
KITopen
Published
2026-06-26
DOI
https://doi.org/10.5445/ir/1000194634
Primary Topic
Sleep and related disorders
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Do subjective and objective baseline sleep disturbances predict post-traumatic stress disorder treatment response? A secondary analysis of a randomized controlled trial

Meike Müller‐Engelmann, Regina Steil, Kathlen Priebe, Nikolaus Kleindienst et al.
KITopen
Sleep and related disorders
article

Do subjective and objective baseline sleep disturbances predict post-traumatic stress disorder treatment response? A secondary analysis of a randomized controlled trial

Meike Müller‐Engelmann, Regina Steil, Kathlen Priebe, Nikolaus Kleindienst, Franziska Friedmann, Nikola Schoofs, Thomas Fydrich, Salomé Porten, Philip Santangelo, Ulrich Ebner-Priemer
article en

Abstract

$\textbf{Background:}$ Sleep disturbances are highly prevalent in individuals with post-traumatic stress disorder (PTSD) and might interfere with trauma-focused treatments by disrupting memory consolidation, extinction and safety learning. However, evidence on the impact of sleep deficits on PTSD treatments remains inconclusive. $\textbf{Objective:}$ This study conducted a secondary analysis of a randomized controlled trial comparing cognitive processing therapy (CPT) and dialectical behaviour therapy for PTSD (DBT-PTSD) in women with PTSD. We examined whether subjective and objective baseline sleep disturbances predicted PTSD symptom reduction after up to 15 months of outpatient treatment, whether depression moderated this relationship, and whether effects differed for CPT and DBT-PTSD. $\textbf{Method:}$ Sleep was assessed in n = 178 women using actigraphy, sleep diaries, and the Pittsburgh sleep quality index (PSQI), applying linear mixed models for each sleep measure. $\textbf{Results:}$ Subjective sleep disturbances as measured in the PSQI did not significantly predict overall treatment outcomes for PTSD (p = .140). Additionally, depressive symptoms did not moderate this relationship (p = .469), and the effect did not differ for CPT and DBT-PTSD (p = .086). The same was found for sleep diary and actigraphy assessments. $\textbf{Conclusions:}$ These findings suggest that sleep disturbances do not hinder the effectiveness of long-term trauma-focused PTSD treatment in women with complex trauma presentations, implying that sleep-specific interventions may not be a prerequisite for initiating trauma-focused treatment in this population.

KITopen
Good health and well-being
Openalex Percentile: Top 5%
Sleep and related disorders
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.