Response to “Comment on ‘Three-Principal-Substrate SERS Profiling Enables Reliable Screening of Serum Biomarkers: A General Approach’ ”
We sincerely thank Alois Bonifacio and co-workers for their valuable comments on our work entitled "Three-Principal-Substrate SERS Profiling Enables Reliable Screening of Serum Biomarkers: A General Approach" (Anal. Chem. 2026, 98, 9273; DOI: 10.1021/acs.analchem.5c08093). The present response aims to address the concerns raised regarding the interpretation of SERS band assignments, as well as the suggestion that more rigorous validation of differential spectral features should be pursued in future studies.
Authors
- W M Wang
- Zhengyuan Zhao (ORCID: https://orcid.org/0009-0007-9231-1648)
- Xuecheng Dong (ORCID: https://orcid.org/0000-0003-4644-4419)
- Zhengjun Zhang
Institutions
- Division of Materials Science and Engineering (AU)
- Advanced Energy Materials (United States) (US)
- Tsinghua University (CN)
Publication Details
- Journal
- Analytical Chemistry
- Published
- 2026-06-25
- DOI
- https://doi.org/10.1021/acs.analchem.6c02877
- Primary Topic
- Spectroscopy Techniques in Biomedical and Chemical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00