Myocarditis revealing a pheochromocytoma: When the heart gives the adrenal gland away

Introduction: Pheochromocytoma is a rare tumour that secretes catecholamines and can present with a variety of complications, including severe cardiovascular complications such as myocarditis and cardiomyopathy. Early diagnosis of these atypical presentations is essential for prompt management. Case report: We report the case of a 62-year-old patient, a chronic smoker, admitted for management of a deterioration in his general condition. He presented with asthenia, weight loss, sweating, palpitations, headaches, abdominal pain and vomiting. Clinical examination revealed a hypertensive crisis (250/130 mmHg), tachycardia, proximal muscle weakness and abnormalities on the electrocardiogram. Laboratory tests revealed an infectious syndrome, acute renal failure and elevated cardiac biomarkers. Plasma methoxylated derivatives were very high. Imaging showed a left adrenal mass with central necrosis. The diagnosis was severe myocarditis with rhabdomyolysis secondary to a pheochromocytoma. Management involved antihypertensive treatment, antibiotic therapy and plans for adrenal surgery. Conclusion: This case highlights the importance of considering pheochromocytoma in the presence of cardiac symptoms that may sometimes be atypical, such as acute myocarditis, particularly when accompanied by a hypertensive crisis. Early diagnosis enables optimal management and improves the prognosis.

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Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-06-25
DOI
https://doi.org/10.5281/zenodo.20843423
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
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article

Myocarditis revealing a pheochromocytoma: When the heart gives the adrenal gland away

A. Meftah, R. Dassoufi, H. Baïzri, A. Idrissi et al.
Zenodo (CERN European Organization for Nuclear Research)
Adrenal and Paraganglionic Tumors
article

Myocarditis revealing a pheochromocytoma: When the heart gives the adrenal gland away

A. Meftah, R. Dassoufi, H. Baïzri, A. Idrissi, I. Chaari, H. El jadi, E. Niyogushima
article en

Abstract

Introduction: Pheochromocytoma is a rare tumour that secretes catecholamines and can present with a variety of complications, including severe cardiovascular complications such as myocarditis and cardiomyopathy. Early diagnosis of these atypical presentations is essential for prompt management. Case report: We report the case of a 62-year-old patient, a chronic smoker, admitted for management of a deterioration in his general condition. He presented with asthenia, weight loss, sweating, palpitations, headaches, abdominal pain and vomiting. Clinical examination revealed a hypertensive crisis (250/130 mmHg), tachycardia, proximal muscle weakness and abnormalities on the electrocardiogram. Laboratory tests revealed an infectious syndrome, acute renal failure and elevated cardiac biomarkers. Plasma methoxylated derivatives were very high. Imaging showed a left adrenal mass with central necrosis. The diagnosis was severe myocarditis with rhabdomyolysis secondary to a pheochromocytoma. Management involved antihypertensive treatment, antibiotic therapy and plans for adrenal surgery. Conclusion: This case highlights the importance of considering pheochromocytoma in the presence of cardiac symptoms that may sometimes be atypical, such as acute myocarditis, particularly when accompanied by a hypertensive crisis. Early diagnosis enables optimal management and improves the prognosis.

Zenodo (CERN European Organization for Nuclear Research)
Cadi Ayyad University (MA), Centre Hospitalier Universitaire Mohammed VI (MA), Razi Hospital (IR), Hôpital Militaire Avicenne (MA)
Good health and well-being
Openalex Percentile: Top 6%
Adrenal and Paraganglionic Tumors
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Myocarditis revealing a pheochromocytoma: When the heart gives the adrenal gland away — A. Meftah, R. Dassoufi, et al. · Zenodo (CERN European Organization for Nuclear Research) (2026) | TGRS Research Map | TGRS