Atypical Disseminated Herpes Zoster With Rapid Spread in an Older Adult

Disseminated herpes zoster is an uncommon and severe presentation of varicella zoster virus reactivation that may involve widespread cutaneous lesions and atypical distributions. Although it is more frequently observed in immunocompromised individuals, it can also occur in immunocompetent patients, particularly in older adults, and may present with generalized eruptions that resemble varicella. We report a case of atypical disseminated herpes zoster with involvement of the gluteal region, genitalia, and bilateral lower extremities in an immunocompetent patient, highlighting an unusual clinical presentation and the importance of early recognition.

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Publication Details

Journal
Cureus
Published
2026-06-25
DOI
https://doi.org/10.7759/cureus.111509
Primary Topic
Herpesvirus Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Atypical Disseminated Herpes Zoster With Rapid Spread in an Older Adult

Gokul Paidi, Shivangi Yadav, Gifty Thomas, Gandhy Montalvo Rosales et al.
Cureus
Herpesvirus Infections and Treatments
article

Atypical Disseminated Herpes Zoster With Rapid Spread in an Older Adult

Gokul Paidi, Shivangi Yadav, Gifty Thomas, Gandhy Montalvo Rosales, Jashvini Amirthalingam, Pushpa Yadav
article en

Abstract

Disseminated herpes zoster is an uncommon and severe presentation of varicella zoster virus reactivation that may involve widespread cutaneous lesions and atypical distributions. Although it is more frequently observed in immunocompromised individuals, it can also occur in immunocompetent patients, particularly in older adults, and may present with generalized eruptions that resemble varicella. We report a case of atypical disseminated herpes zoster with involvement of the gluteal region, genitalia, and bilateral lower extremities in an immunocompetent patient, highlighting an unusual clinical presentation and the importance of early recognition.

Cureus
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Openalex Percentile: Top 7%
Herpesvirus Infections and Treatments
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