Adaptive islet biology and comprehensive incretin physiology: Emerging perspectives from Asia and Europe
Adaptive islet biology and incretin physiology provide a framework linking diverse diabetes phenotypes, with advances in β-cell stress adaptation, intra-islet communication, receptor-resolved biology, and β-cell mass imaging. By integrating clinical perspectives from Asia and Europe with multiscale islet-cell biology, these insights may support mechanism-based and more targeted therapeutic approaches.
Authors
- Daniela Nasteska (ORCID: https://orcid.org/0000-0002-8996-5102)
- David J. Hodson (ORCID: https://orcid.org/0000-0002-8641-8568)
- Takaaki Murakami (ORCID: https://orcid.org/0000-0003-3844-1138)
- Daisuke Yabe (ORCID: https://orcid.org/0000-0002-5334-7687)
- Yutaka Seino
- Yuji Yamazaki (ORCID: https://orcid.org/0009-0007-5876-8695)
Institutions
- Kyoto University (JP)
- Kansai Electric Power (Japan) (JP)
- Kansai Electric Power Hospital (JP)
- Oxford Centre for Diabetes, Endocrinology and Metabolism (GB)
Publication Details
- Journal
- Journal of Diabetes Investigation
- Published
- 2026-06-25
- DOI
- https://doi.org/10.1111/jdi.70378
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00