Chronic Spontaneous Coronary Artery Dissection in a Young Woman Managed With Coronary Artery Bypass Grafting: A Case Report With Literature Review

ABSTRACT Spontaneous coronary artery dissection (SCAD) is an uncommon, non‐atherosclerotic cause of acute coronary syndrome, typically occurring in young to middle‐aged women. Although most cases resolve spontaneously with conservative therapy, a small proportion develop chronic dissections that require revascularization. We report the case of a 39‐year‐old Ethiopian woman with a 7‐year history of coronary artery disease who had been managed medically but presented with worsening exertional chest pain. Invasive coronary angiography during the current presentation demonstrated a long‐segment dissection of the left anterior descending (LAD) artery along with a 60% mid‐right coronary artery (RCA) stenosis of uncertain etiology. Coronary angiography performed 1 year and 5 months earlier had shown a proximal LAD dissection and a 50% mid‐RCA stenosis. Despite prolonged medical therapy, her symptoms persisted. She subsequently underwent successful coronary artery bypass grafting (CABG), with an uneventful perioperative course. This case highlights the rare occurrence of chronic SCAD with persistent ischemia despite conservative therapy. It underscores the potential role of follow‐up coronary angiography in selected symptomatic patients to guide individualized management. CABG may be considered in refractory cases when medical therapy fails and PCI is not feasible or unlikely to achieve durable revascularization.

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Journal
Clinical Case Reports
Published
2026-06-25
DOI
https://doi.org/10.1002/ccr3.72996
Primary Topic
Cardiovascular Issues in Pregnancy
Type
article
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article

Chronic Spontaneous Coronary Artery Dissection in a Young Woman Managed With Coronary Artery Bypass Grafting: A Case Report With Literature Review

Gashayeneh Genetu Tiruneh, Jim Kauten, Clifford J. Kavinsky, Obsinet Merid et al.
Clinical Case Reports
Cardiovascular Issues in Pregnancy
article

Chronic Spontaneous Coronary Artery Dissection in a Young Woman Managed With Coronary Artery Bypass Grafting: A Case Report With Literature Review

Gashayeneh Genetu Tiruneh, Jim Kauten, Clifford J. Kavinsky, Obsinet Merid, Getu Kusa Wakoya, Gashaw Solela, Chala Fekadu Oljira, Desalew Mekonnen, Dagmawit Mesfin Tasew, Adane Petros, Nish Patel, Tesfaye Telila, Siraj Kemal Mussa, Tesfamariam Aklilu Betemariam
article en

Abstract

ABSTRACT Spontaneous coronary artery dissection (SCAD) is an uncommon, non‐atherosclerotic cause of acute coronary syndrome, typically occurring in young to middle‐aged women. Although most cases resolve spontaneously with conservative therapy, a small proportion develop chronic dissections that require revascularization. We report the case of a 39‐year‐old Ethiopian woman with a 7‐year history of coronary artery disease who had been managed medically but presented with worsening exertional chest pain. Invasive coronary angiography during the current presentation demonstrated a long‐segment dissection of the left anterior descending (LAD) artery along with a 60% mid‐right coronary artery (RCA) stenosis of uncertain etiology. Coronary angiography performed 1 year and 5 months earlier had shown a proximal LAD dissection and a 50% mid‐RCA stenosis. Despite prolonged medical therapy, her symptoms persisted. She subsequently underwent successful coronary artery bypass grafting (CABG), with an uneventful perioperative course. This case highlights the rare occurrence of chronic SCAD with persistent ischemia despite conservative therapy. It underscores the potential role of follow‐up coronary angiography in selected symptomatic patients to guide individualized management. CABG may be considered in refractory cases when medical therapy fails and PCI is not feasible or unlikely to achieve durable revascularization.

Clinical Case ReportsVol. 14(7)
Loyola University Medical Center (US), Piedmont Atlanta Hospital (US), The Cardiac and Vascular Institute (US), Addis Ababa University (ET), Morehouse School of Medicine (US)
Openalex Percentile: Top 8%
Cardiovascular Issues in Pregnancy
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