Cognitive Bioprediction and Moral Responsibility: Foreseeability, Control and the Ethics of Anticipated Cognitive Impairment

Bioprediction uses biomedical data, biomarkers, and algorithmic tools to forecast future physiological states or impairments. As predictive technologies increasingly enable individuals to anticipate loss of cognitive capacity before it occurs, they raise a fundamental ethical question: how should moral responsibility be assessed when impairment becomes foreseeable in advance of its onset? We argue that biopredictive technologies can alter both the epistemic and control conditions that ground moral responsibility. In some cases, this generates obligations to respond to predictive warnings of cognitive decline; in more limited circumstances, it may also ground obligations to acquire and use biopredictive technologies where these represent a proportionate and least restrictive means of risk reduction. We further argue that emerging individual responsibilities generate corresponding obligations for states. Where access to biopredictive technologies is necessary to meet morally significant expectations of risk management, fairness, and legitimacy require attention to affordability, accessibility, and institutional support.

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Publication Details

Journal
AJOB Neuroscience
Published
2026-06-25
DOI
https://doi.org/10.1080/21507740.2026.2686620
Primary Topic
Neuroethics, Human Enhancement, Biomedical Innovations
Type
article
Field-Weighted Citation Impact
0.00

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article

Cognitive Bioprediction and Moral Responsibility: Foreseeability, Control and the Ethics of Anticipated Cognitive Impairment

Danièle Pacaud, Tasmia Hai, Sinead Prince, Matthew Baum et al.
AJOB Neuroscience
Neuroethics, Human Enhancement, Biomedical Innovations
article

Cognitive Bioprediction and Moral Responsibility: Foreseeability, Control and the Ethics of Anticipated Cognitive Impairment

Danièle Pacaud, Tasmia Hai, Sinead Prince, Matthew Baum, Fergus Cameron, Jamie Walvisch, Julian Savulescu
article en

Abstract

Bioprediction uses biomedical data, biomarkers, and algorithmic tools to forecast future physiological states or impairments. As predictive technologies increasingly enable individuals to anticipate loss of cognitive capacity before it occurs, they raise a fundamental ethical question: how should moral responsibility be assessed when impairment becomes foreseeable in advance of its onset? We argue that biopredictive technologies can alter both the epistemic and control conditions that ground moral responsibility. In some cases, this generates obligations to respond to predictive warnings of cognitive decline; in more limited circumstances, it may also ground obligations to acquire and use biopredictive technologies where these represent a proportionate and least restrictive means of risk reduction. We further argue that emerging individual responsibilities generate corresponding obligations for states. Where access to biopredictive technologies is necessary to meet morally significant expectations of risk management, fairness, and legitimacy require attention to affordability, accessibility, and institutional support.

AJOB Neuroscience
Brigham and Women's Hospital (US), Royal Children's Hospital (AU), National University of Singapore (SG), University of Calgary (CA), The University of Western Australia (AU), Royal Ottawa Mental Health Centre (CA), Harvard University Press (US), University of Oxford (GB), Children's Hospital Research Institute of Manitoba (CA), Murdoch Children's Research Institute (AU), University of Manitoba (CA), McGill University (CA)
Wellcome Trust, National University of Singapore
Openalex Percentile: Top 6%
Neuroethics, Human Enhancement, Biomedical Innovations
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