<i>Notes from the Field:</i> Drug Overdose Deaths in Hotels and Motels — United States, 2022–2024

In 2024, at least 2,327 drug overdose deaths occurred in hotels and motels, the second most common location after houses and apartments (1).Analyses of overdose locations can help jurisdictions make decisions regarding optimal distribution of limited local resources for prevention, including opioid overdose reversal medications such as naloxone, and identify local options for substance use disorder treatment to prevent overdose deaths among residents (2-4).However, analyses of overdose locations do not always explicitly include hotels and motels (4).Public health interventions can benefit from improved understanding of the circumstances surrounding drug overdose deaths in hotels and motels, including whether local resources to prevent overdoses among residents might be used in these locations.CDC analyzed data from its State Unintentional Drug Overdose Response System (SUDORS) to characterize drug overdose deaths that occurred in hotels and motels during 2022-2024. Investigation and Outcomes Data Source and AnalysisSUDORS collects data on overdose deaths that were unintentional or of undetermined intent from death certificates, postmortem toxicology reports, and reports with contextual data about the circumstances of the death (e.g., coroner or medical examiner investigation reports, emergency medical services records, and medical records).CDC conducted a descriptive analysis of 2022-2024 SUDORS data from 47 jurisdictions (46 states and the District of Columbia).*The objective of this analysis was to describe certain characteristics of overdose deaths that occur in hotels and motels, including the demographic characteristics of * Restricted to deaths with contextual data from jurisdictions with death certificates and contextual data for ≥75% of deaths for at least one 6-month reporting period during 2022-2024 in the following 47 jurisdictions: Alabama, Alaska,