Invariance property of the latent weibull test for comparing ordinal data

The latent Weibull model has recently been reported to be a superior testing tool for comparing two treatments with ordinal responses. Response-adaptive procedures were also developed for the design of these clinical studies. The test statistic is constructed on the basis of the latent Weibull model. Due to the need for model identification, the estimation procedure relies on the selection of one of the treatments as a reference, which is modeled by a standard Weibull distribution. However, it is unclear whether the choice of the reference affects the test procedure. The objective of this short paper is to provide a theoretical proof of this crucial invariance property, under which the test conclusion is invariant to the choice of the reference. A clinical example is also used to illustrate the invariance property.

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Publication Details

Journal
Communication in Statistics- Theory and Methods
Published
2026-06-25
DOI
https://doi.org/10.1080/03610926.2026.2687766
Primary Topic
Statistical Methods in Clinical Trials
Type
article
Field-Weighted Citation Impact
0.00

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article

Invariance property of the latent weibull test for comparing ordinal data

Junjiang Zhong, Siu Hung Cheung, Tongyu Lu, Yueqiong Lin
Communication in Statistics- Theory and Methods
Statistical Methods in Clinical Trials
article

Invariance property of the latent weibull test for comparing ordinal data

Junjiang Zhong, Siu Hung Cheung, Tongyu Lu, Yueqiong Lin
article en

Abstract

The latent Weibull model has recently been reported to be a superior testing tool for comparing two treatments with ordinal responses. Response-adaptive procedures were also developed for the design of these clinical studies. The test statistic is constructed on the basis of the latent Weibull model. Due to the need for model identification, the estimation procedure relies on the selection of one of the treatments as a reference, which is modeled by a standard Weibull distribution. However, it is unclear whether the choice of the reference affects the test procedure. The objective of this short paper is to provide a theoretical proof of this crucial invariance property, under which the test conclusion is invariant to the choice of the reference. A clinical example is also used to illustrate the invariance property.

Communication in Statistics- Theory and Methods
Chinese University of Hong Kong (HK), China Jiliang University (CN), Xiamen University of Technology (CN), Fuzhou University (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 5%
Statistical Methods in Clinical Trials
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