Understanding the Predictors of Self‐Perceived Burden in Patients With Liver Cancer

Liver cancer poses a serious global health burden, with China experiencing particularly high incidence and mortality rates. Treatment complexity and severe side effects often impair patients' quality of life, leading to self-perceived burden (SPB) stemming from care dependency, financial pressure, and emotional distress. This cross-sectional study of 139 patients with liver cancer explored predictors of SPB using multiple linear regression. Results showed that 97.82% of the participants experienced SPB (mean = 63.58 ± 15.33). Unemployment before illness, chemotherapy, use of confrontation, and fantasy coping strategies were significant predictors of SPB. Findings highlight the urgent need for targeted interventions to alleviate SPB and enhance patients' quality of life.