A Rare Case of Abdominal Wall Schwannoma

Schwannomas are relatively uncommon benign tumors of the peripheral nerve sheaths most commonly found in the head, neck, and extremities. Very few reported cases of abdominal wall schwannomas exist. We report the case of a 71-year-old man with a left-sided abdominal wall mass who subsequently underwent surgical excision with final histopathology demonstrating a cellular schwannoma. Histopathological analysis confirmed the diagnosis, revealing immunoreactivity for S100, SOX10, and vimentin while being negative for smooth muscle actin, CD34, and desmin. The Ki-67 proliferative index was 5%. These findings are consistent with a schwannoma. In this study, we emphasize the importance of considering schwannoma when evaluating soft tissue masses, even in atypical locations. This unusual finding adds to the available limited literature describing abdominal wall schwannomas.

Authors

Publication Details

Journal
Cureus
Published
2026-06-25
DOI
https://doi.org/10.7759/cureus.111498
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
Field-Weighted Citation Impact
0.00

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article

A Rare Case of Abdominal Wall Schwannoma

Michael P. O’Leary, Mary E. Londoño, Andrea J Lee, Vanessa Le et al.
Cureus
Neurofibromatosis and Schwannoma Cases
article

A Rare Case of Abdominal Wall Schwannoma

Michael P. O’Leary, Mary E. Londoño, Andrea J Lee, Vanessa Le, Oliver Eng
article en

Abstract

Schwannomas are relatively uncommon benign tumors of the peripheral nerve sheaths most commonly found in the head, neck, and extremities. Very few reported cases of abdominal wall schwannomas exist. We report the case of a 71-year-old man with a left-sided abdominal wall mass who subsequently underwent surgical excision with final histopathology demonstrating a cellular schwannoma. Histopathological analysis confirmed the diagnosis, revealing immunoreactivity for S100, SOX10, and vimentin while being negative for smooth muscle actin, CD34, and desmin. The Ki-67 proliferative index was 5%. These findings are consistent with a schwannoma. In this study, we emphasize the importance of considering schwannoma when evaluating soft tissue masses, even in atypical locations. This unusual finding adds to the available limited literature describing abdominal wall schwannomas.

Cureus
U.S. Department of Veterans Affairs, University of California, Irvine
Openalex Percentile: Top 7%
Neurofibromatosis and Schwannoma Cases
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