¹⁸F-FDG PET/CT in the evaluation of femoral head osteonecrosis in patients with lymphoma.

OBJECTIVE: F-FDG) positron emission tomography (PET)/CT and explore whether PET/CT can raise suspicion for ONFH in patients with lymphoma. METHODS: ) of ONFH was measured. The staging and extent of ONFH, and other bone involvements, were visually assessed. Lymphoma disease status was evaluated using the Deauville criteria. RESULTS: F-FDG uptake patterns, all stage 1 lesions showed normal uptake; among stage 2 lesions, 11 showed increased uptake, 5 showed peripheral increased with central decreased uptake, 2 showed decreased uptake, and 6 showed normal uptake; all stage 3-4 lesions demonstrated increased uptake. On CT, the extent of all stage 2-4 lesions matched MRI findings. Nine patients had osteonecrosis in other bones, including the humeral heads (n = 9), bilateral iliac bones (n = 6), and vertebrae/ribs/scapulae (n = 1). CONCLUSIONS: F-FDG uptake and may be accompanied by involvement of other bones. PET/CT may raise suspicion for ONFH and detect multiple bone involvements during lymphoma assessment.