Utilizing Lead aVR QRS Morphology to Localize Abnormal Substrates in Arrhythmogenic Right Ventricular Cardiomyopathy
Accurate, noninvasive markers reflecting epicardial scar distribution and guide ablation strategy in arrhythmogenic right ventricular cardiomyopathy remain limited.In this study, the R/Q ratio and morphology in electrocardiography (ECG) lead aVR were associated with right ventricular epicardial scar distribution and may help identify patients who require broader endocardial or epicardial ablation.These electrocardiographic indicators were also associated with right ventricular dysfunction and markers of arrhythmic vulnerability.Our findings suggest a simple ECG-based approach that may assist substrate characterization, procedural planning, and risk assessment.
Authors
- Fa‐Po Chung (ORCID: https://orcid.org/0000-0001-8960-1301)
- Shih‐Lin Chang (ORCID: https://orcid.org/0000-0001-7030-8471)
- Tze‐Fan Chao (ORCID: https://orcid.org/0000-0002-6587-3094)
- Ting‐Yung Chang (ORCID: https://orcid.org/0000-0002-4111-7067)
- Jo‐Nan Liao (ORCID: https://orcid.org/0000-0001-8033-127X)
- Ta‐Chuan Tuan (ORCID: https://orcid.org/0000-0002-0534-3729)
- Shin‐Huei Liu (ORCID: https://orcid.org/0000-0001-9052-7858)
- Yu‐Feng Hu (ORCID: https://orcid.org/0000-0001-5715-2070)
- Chiao‐Chin Lee (ORCID: https://orcid.org/0000-0002-5220-7551)
- Yenn‐Jiang Lin (ORCID: https://orcid.org/0000-0001-8395-1052)
- Guan‐Yi Li (ORCID: https://orcid.org/0000-0002-0550-8837)
- Lo-Chieh Ling (ORCID: https://orcid.org/0000-0003-4734-6191)
- Chin‐Yu Lin (ORCID: https://orcid.org/0000-0003-3282-7523)
- Ling Kuo (ORCID: https://orcid.org/0000-0002-8604-6151)
- Yu‐Shan Huang (ORCID: https://orcid.org/0000-0003-3950-4786)
- Chih‐Min Liu (ORCID: https://orcid.org/0000-0002-7235-273X)
- Cheng‐I Wu (ORCID: https://orcid.org/0000-0002-5879-4136)
- Shih‐Ann Chen (ORCID: https://orcid.org/0000-0001-9085-0823)
- Ming-Jen Kuo
- Li-Wei Lo (ORCID: https://orcid.org/0000-0001-9042-3493)
- Wen-Po Fan (ORCID: https://orcid.org/0000-0002-2666-7271)
Institutions
- National Yang Ming Chiao Tung University (TW)
- National Chung Hsing University (TW)
- China Medical University (TW)
- Taipei Veterans General Hospital (TW)
- Taichung Veterans General Hospital (TW)
- National Defense Medical Center (TW)
Publication Details
- Journal
- Korean Circulation Journal
- Published
- 2026-06-24
- DOI
- https://doi.org/10.4070/kcj.2025.0547
- Primary Topic
- Cardiovascular Effects of Exercise
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Science and Technology, Taiwan
- Tri-Service General Hospital
- Taipei Veterans General Hospital