Design, synthesis, and antibacterial activity study of pyrroloquinazoline diamine derivatives
as a promising lead for developing novel, broad-spectrum DHFR inhibitors with a low resistance risk.
Authors
- Yuanying Jiang (ORCID: https://orcid.org/0000-0001-6578-6225)
- Qiang Fu (ORCID: https://orcid.org/0000-0001-9030-366X)
- 赫卫清
- Xunli Xiao (ORCID: https://orcid.org/0000-0002-6402-2220)
- Jiawei Li (ORCID: https://orcid.org/0000-0001-5646-198X)
- Ying Zheng (ORCID: https://orcid.org/0000-0002-5100-9983)
- Xianqing Deng (ORCID: https://orcid.org/0009-0001-7688-7491)
- Jieya Shang
- Mingxia Song
- Yajing Tian
- Muchun Cheng
- Xinyu Chen
- Can Yan
Institutions
- Tongji University (CN)
- Jinggangshan University (CN)
Publication Details
- Journal
- Journal of Enzyme Inhibition and Medicinal Chemistry
- Published
- 2026-06-24
- DOI
- https://doi.org/10.1080/14756366.2026.2690351
- Primary Topic
- Quinazolinone synthesis and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China