No association of prior administration of selected vaccines with lymphoma prognosis
BACKGROUND: While some vaccines appear to be associated with lower risk of lymphoma, their impact on outcomes is largely unknown. METHODS: Data from a large prospective lymphoma cohort study was utilized to estimate associations of self-reported history of vaccination against hepatitis A, hepatitis B, influenza, and yellow fever with event-free survival (EFS) and overall survival (OS) using Cox proportional hazard models. RESULTS: None of the vaccines were associated with EFS (HRs 0.77-1.00) or OS (HRs 0.96-1.04). Similarly, there were no significant associations between the vaccines and outcome for each lymphoma subtype. CONCLUSIONS: Prior vaccination against selected viruses was not associated with EFS or OS among patients with lymphoma. IMPACT: We did not find evidence for an impact of prior vaccination on lymphoma prognosis.
Authors
- Thomas E. Witzig (ORCID: https://orcid.org/0000-0002-4215-6500)
- Carrie A. Thompson (ORCID: https://orcid.org/0000-0002-4518-2309)
- George Cholack (ORCID: https://orcid.org/0000-0001-6774-7326)
- Thomas Matthew Habermann (ORCID: https://orcid.org/0000-0003-3532-9132)
- Anne J. Novak (ORCID: https://orcid.org/0000-0002-7904-1651)
- Eric Mou (ORCID: https://orcid.org/0000-0002-9865-4517)
- Matthew J. Maurer (ORCID: https://orcid.org/0000-0002-1867-0526)
- Stephen M. Ansell (ORCID: https://orcid.org/0000-0003-1244-6758)
- Susan L. Slager (ORCID: https://orcid.org/0000-0002-5173-4712)
- James R. Cerhan (ORCID: https://orcid.org/0000-0002-7482-178X)
- Raphael Mwangi (ORCID: https://orcid.org/0000-0002-9004-9099)
- Andrew L. Feldman (ORCID: https://orcid.org/0000-0001-5009-4808)
- Yucai Wang (ORCID: https://orcid.org/0000-0002-1576-8341)
- Melissa C. Larson (ORCID: https://orcid.org/0000-0002-5430-8161)
- Dennis P. Robinson (ORCID: https://orcid.org/0009-0000-4812-9397)
- Verena Hinder
Institutions
- University of Iowa (US)
- Mayo Clinic (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Cancer Epidemiology Biomarkers & Prevention
- Published
- 2026-06-24
- DOI
- https://doi.org/10.1158/1055-9965.epi-26-0427
- Primary Topic
- Viral-associated cancers and disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00