Thresholds of the Invasive Physiological Indices Associated with Anginal Symptoms and an Impaired Exercise Capacity in Patients with Chronic Coronary Syndrome
Objective: The thresholds of the fractional flow reserve (FFR) and non-hyperemic pressure ratios (NHPRs) for identifying myocardial ischemia and guiding coronary revascularization are well-established (FFR ≤ 0.80 and NHPRs ≤ 0.89). However, the values associated with patient symptoms remain unclear. This study aimed to identify the thresholds associated with anginal symptoms and an impaired exercise capacity in patients with chronic coronary syndrome (CCS).
Authors
- Daisuke Higashioka (ORCID: https://orcid.org/0000-0002-4944-744X)
- Natsuki Higashimoto
- Akira Taruya (ORCID: https://orcid.org/0000-0003-4457-3700)
- Yasushi Ino (ORCID: https://orcid.org/0000-0003-0108-9150)
- Toshio Imanishi (ORCID: https://orcid.org/0000-0003-3355-9196)
- Hiroki Emori
- Yasutsugu Shiono (ORCID: https://orcid.org/0000-0003-4150-0899)
- Masahiro Takahata (ORCID: https://orcid.org/0000-0002-5399-0525)
- Toshikazu Hashizume
- Teruaki Wada (ORCID: https://orcid.org/0009-0009-8637-6853)
- S Kuki
- Y Ozaki
- Atsushi Tanaka
- Hironori Kitabata
Institutions
- Wakayama Medical University (JP)
- Hidaka Hospital (JP)
- Minami Wakayama Medical Center (JP)
- Hashimoto Municipal Hospital (JP)
- Kinan Hospital (JP)
Publication Details
- Journal
- Journal of Coronary Artery Disease
- Published
- 2026-06-24
- DOI
- https://doi.org/10.7793/jcad.32.26-00005
- Primary Topic
- Cardiovascular and exercise physiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00