Steroid Cell Tumor of the Ovary Presenting With Postmenopausal Bleeding and Hyperandrogenism: A Case Report

Steroid cell tumors of the ovary are rare, often hormonally active neoplasms that may present with features of hyperandrogenism. We report the case of a 60-year-old woman who initially presented with postmenopausal bleeding and a reassuringly thin endometrium, with symptoms attributed to hormone replacement therapy. Over time, the development of progressive hirsutism and persistently elevated serum testosterone levels prompted further investigation. Multidisciplinary team involvement, including endocrinology input, was pivotal in identifying a suspected androgen-secreting ovarian tumor and guiding definitive management. Bilateral salpingo-oophorectomy confirmed a steroid cell tumor of the left ovary, International Federation of Gynecology and Obstetrics (FIGO) stage IA, with complete biochemical and clinical resolution. This case highlights the importance of reassessing postmenopausal patients with evolving hyperandrogenic features despite initially reassuring findings.

Authors

Publication Details

Journal
Cureus
Published
2026-06-24
DOI
https://doi.org/10.7759/cureus.111421
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Steroid Cell Tumor of the Ovary Presenting With Postmenopausal Bleeding and Hyperandrogenism: A Case Report

S. Sumi, Supreet Mahurkar, Jaya Cherian
Cureus
Ovarian cancer diagnosis and treatment
article

Steroid Cell Tumor of the Ovary Presenting With Postmenopausal Bleeding and Hyperandrogenism: A Case Report

S. Sumi, Supreet Mahurkar, Jaya Cherian
article en

Abstract

Steroid cell tumors of the ovary are rare, often hormonally active neoplasms that may present with features of hyperandrogenism. We report the case of a 60-year-old woman who initially presented with postmenopausal bleeding and a reassuringly thin endometrium, with symptoms attributed to hormone replacement therapy. Over time, the development of progressive hirsutism and persistently elevated serum testosterone levels prompted further investigation. Multidisciplinary team involvement, including endocrinology input, was pivotal in identifying a suspected androgen-secreting ovarian tumor and guiding definitive management. Bilateral salpingo-oophorectomy confirmed a steroid cell tumor of the left ovary, International Federation of Gynecology and Obstetrics (FIGO) stage IA, with complete biochemical and clinical resolution. This case highlights the importance of reassessing postmenopausal patients with evolving hyperandrogenic features despite initially reassuring findings.

Cureus
Good health and well-being
Openalex Percentile: Top 6%
Ovarian cancer diagnosis and treatment
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