Force Distribution and Contact Mechanics in Mini-Tablet Compaction: A Discrete Element Method Study

Abstract Purpose The purpose of this study was to investigate how powder fill weight, particle size, and particle size distribution influence force transmission and compaction behavior of powders during compaction within narrow die cavities. Methods Discrete element method simulations were used to model confined powder compaction. Monodisperse and polydisperse systems were analyzed by varying particle size, size distribution breadth, and fill weight. Compaction force–displacement behavior was examined together with particle-level normal, tangential, and cohesive forces, including their axial and radial spatial distributions. Results Particle size had a stronger influence on force heterogeneity than fill weight within the range examined, with larger particles generating higher and more heterogeneous contact forces. Force distributions were positively skewed, indicating load localization within force chains. Normal and tangential forces were highest near the die wall, reflecting strong confinement effects. While individual particle forces followed similar size-dependent trends across different size distributions, narrow distributions required higher compaction forces due to localized load-bearing structures, whereas wider distributions promoted more uniform force sharing and lower resistance to compaction. Conclusions The results demonstrated that macroscopic compaction behavior was governed by the organization of force networks rather than particle-scale force magnitudes alone, highlighting the critical roles of particle size, polydispersity, and confinement effects in powder compaction.

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Publication Details

Journal
Pharmaceutical Research
Published
2026-06-18
DOI
https://doi.org/10.1007/s11095-026-04127-y
Primary Topic
Powder Metallurgy Techniques and Materials
Type
article
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article

Force Distribution and Contact Mechanics in Mini-Tablet Compaction: A Discrete Element Method Study

Tran Trong Bien, Tze Ning Hiew, Bodhisattwa Chaudhuri, Saeed Najafian
Pharmaceutical Research
Powder Metallurgy Techniques and Materials
article

Force Distribution and Contact Mechanics in Mini-Tablet Compaction: A Discrete Element Method Study

Tran Trong Bien, Tze Ning Hiew, Bodhisattwa Chaudhuri, Saeed Najafian
article en

Abstract

Abstract Purpose The purpose of this study was to investigate how powder fill weight, particle size, and particle size distribution influence force transmission and compaction behavior of powders during compaction within narrow die cavities. Methods Discrete element method simulations were used to model confined powder compaction. Monodisperse and polydisperse systems were analyzed by varying particle size, size distribution breadth, and fill weight. Compaction force–displacement behavior was examined together with particle-level normal, tangential, and cohesive forces, including their axial and radial spatial distributions. Results Particle size had a stronger influence on force heterogeneity than fill weight within the range examined, with larger particles generating higher and more heterogeneous contact forces. Force distributions were positively skewed, indicating load localization within force chains. Normal and tangential forces were highest near the die wall, reflecting strong confinement effects. While individual particle forces followed similar size-dependent trends across different size distributions, narrow distributions required higher compaction forces due to localized load-bearing structures, whereas wider distributions promoted more uniform force sharing and lower resistance to compaction. Conclusions The results demonstrated that macroscopic compaction behavior was governed by the organization of force networks rather than particle-scale force magnitudes alone, highlighting the critical roles of particle size, polydispersity, and confinement effects in powder compaction.

Pharmaceutical Research
University of Iowa (US), University of Connecticut (US)
Openalex Percentile: Top 11%
Powder Metallurgy Techniques and Materials
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Force Distribution and Contact Mechanics in Mini-Tablet Compaction: A Discrete Element Method Study — Tran Trong Bien, Tze Ning Hiew, et al. · Pharmaceutical Research (2026) | TGRS Research Map | TGRS