Long-Term Outcomes After Ischemic Stroke Across Atrial Fibrillation Phenotypes Defined by Detection Timing and Prior Anticoagulation Status

Atrial fibrillation (AF)–associated ischemic stroke is often managed as a single clinical entity; however, prognosis may vary depending on whether AF was detected after the stroke or whether the stroke occurred despite prior oral anticoagulant (OAC) use. We aimed to describe long-term outcomes after ischemic stroke across 3 distinct AF phenotypes: AF complicated by ischemic stroke despite prior anticoagulation (AFIDA), AF complicated by ischemic stroke without prior anticoagulation (OAC-naive AF), and AF detected after stroke (AFDAS).

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Publication Details

Journal
Neurology
Published
2026-06-18
DOI
https://doi.org/10.1212/wnl.0000000000218198
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
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article

Long-Term Outcomes After Ischemic Stroke Across Atrial Fibrillation Phenotypes Defined by Detection Timing and Prior Anticoagulation Status

Masatoshi Koga, Tatsushi Toda, Shuhei Egashira, Yuichi Imanaka et al.
Neurology
Atrial Fibrillation Management and Outcomes
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Long-Term Outcomes After Ischemic Stroke Across Atrial Fibrillation Phenotypes Defined by Detection Timing and Prior Anticoagulation Status

Masatoshi Koga, Tatsushi Toda, Shuhei Egashira, Yuichi Imanaka, Kosuke Inoue
article en

Abstract

Atrial fibrillation (AF)–associated ischemic stroke is often managed as a single clinical entity; however, prognosis may vary depending on whether AF was detected after the stroke or whether the stroke occurred despite prior oral anticoagulant (OAC) use. We aimed to describe long-term outcomes after ischemic stroke across 3 distinct AF phenotypes: AF complicated by ischemic stroke despite prior anticoagulation (AFIDA), AF complicated by ischemic stroke without prior anticoagulation (OAC-naive AF), and AF detected after stroke (AFDAS).

NeurologyVol. 107(1)
Kyoto University (JP), Institute for Security Studies (KE), National Center of Neurology and Psychiatry (JP), National Cerebral and Cardiovascular Center (JP)
Good health and well-being
Openalex Percentile: Top 6%
Atrial Fibrillation Management and Outcomes
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