Endovascular revascularisation of lower-extremity peripheral arterial disease: technical and clinical outcomes in a Vietnamese single-center prospective cohort study

Aims To characterize lesion distribution, procedural strategy, and short-term outcomes after endovascular revascularisation for symptomatic lower-extremity peripheral arterial disease (PAD) in routine Vietnamese practice.Materials and methods This prospective observational cohort included 336 consecutive patients with symptomatic lower-extremity PAD who underwent endovascular revascularisation at a Vietnamese tertiary center from January 2019 to January 2025. Lesions were classified across aorto-iliac, femoropopliteal, and infrapopliteal segments using a TASC-based framework. Outcomes were assessed post-procedure and at 30 days, 3 months, and 6 months.Results Two-level disease was the most common anatomical pattern (47.3%), followed by three-level disease (36.0%). Contralateral femoral access was most frequently used (39.6%), and drug-coated balloons were the most common device strategy (63.7%). Technical success was achieved in 82.4% (95% CI 78.0–86.1). Access-site complications occurred in 5.7% (95% CI 3.6–8.7), in-hospital mortality was 2.9% (95% CI 1.6–5.4), and immediate hemodynamic success was 82.4% (95% CI 78.0–86.1). Landmark-based restenosis rates were 17.9%, 12.4%, and 24.7% at 30 days, 3 months, and 6 months, respectively.Conclusions Endovascular revascularisation was feasible in this real-world Vietnamese PAD cohort, but restenosis remained frequent, supporting structured post-procedural surveillance.