Assessment methodology of pathomorphological regression of melanoma metastasis in the sentinel lymph node after neoadjuvant/perioperative immunotherapy

This methodology has been developed to standardize the pathology evaluation of melanoma metastasis regression in the sentinel lymph node after neoadjuvant/perioperative immunotherapy in patients with stage III resectable cutaneous melanoma. The methodology is intended for use by pathologists, clinical and surgical oncologists, and healthcare quality assessment experts. It can be implemented as a local protocol for pathological examination, as well as integrated into national clinical guidelines and relevant organizational and methodological documents.

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Publication Details

Journal
Russian Journal of Archive of Pathology
Published
2026-06-18
DOI
https://doi.org/10.17116/patol20268803179
Primary Topic
Cutaneous Melanoma Detection and Management
Type
article
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article

Assessment methodology of pathomorphological regression of melanoma metastasis in the sentinel lymph node after neoadjuvant/perioperative immunotherapy

A. Yu. Shamanova, Завалишина Лариса Эдуардовна, Ірина Шапошнікова, Ksenya V. Shelekhova et al.
Russian Journal of Archive of Pathology
Cutaneous Melanoma Detection and Management
article

Assessment methodology of pathomorphological regression of melanoma metastasis in the sentinel lymph node after neoadjuvant/perioperative immunotherapy

A. Yu. Shamanova, Завалишина Лариса Эдуардовна, Ірина Шапошнікова, Ksenya V. Shelekhova, Yа. V. Vishnevskaya, Г. А. Раскин, А. Г. Кудайбергенова, L V Moskvina, O. Yu. Chukhrai, Dmitry A. Tsekatunov, N. A. Savelov, D.O. Zagvozkina
article en

Abstract

This methodology has been developed to standardize the pathology evaluation of melanoma metastasis regression in the sentinel lymph node after neoadjuvant/perioperative immunotherapy in patients with stage III resectable cutaneous melanoma. The methodology is intended for use by pathologists, clinical and surgical oncologists, and healthcare quality assessment experts. It can be implemented as a local protocol for pathological examination, as well as integrated into national clinical guidelines and relevant organizational and methodological documents.

Russian Journal of Archive of PathologyVol. 88(3)
St Petersburg University (RU), Research Medical Center (US), Voronezh Regional Clinical Oncology Center (RU), Saint-Petersburg Medico-Social Institute (RU), Clinical Hospital No. 8 (RU), Russian Medical Academy of Continuous Professional Education (RU), City Clinical Oncology Center (RU), Republican Oncological Clinical Dispensary (RU), Oncological Dispensary No. 2 (RU), Regional Clinical Research (US), State Healthcare Institution "Regional Clinical Oncological Dispensary" (RU), State Budget Institution of Health St. Petersburg Clinical Research Center Specialized Types of Medical Care (RU), Moscow City Oncology Hospital №62 (RU)
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Openalex Percentile: Top 8%
Cutaneous Melanoma Detection and Management
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