Nanomedicine in Cardiovascular Inflammation: Novel Diagnostic and Therapeutic Strategies

Inflammation plays a central role in the pathogenesis and progression of cardiovascular diseases, including atherosclerosis, myocardial infarction and heart failure. Despite advances in conventional diagnostic and therapeutic strategies, limitations in sensitivity, specificity and targeted drug delivery still remain. Nanomedicine has emerged as a promising yet underexplored approach to address these challenges by enabling precise molecular imaging and site-specific therapeutic interventions. This review summarizes current and emerging nanotechnology-based approaches for the diagnosis and treatment of cardiovascular inflammation, highlighting their potential in clinical practice and remaining challenges. In addition, recent advances, including the development of biomimetic nanoplatforms, are discussed, along with future perspectives and the potential integration of artificial intelligence to further enhance precision in cardiovascular medicine.

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Publication Details

Journal
Journal of Personalized Medicine
Published
2026-06-18
DOI
https://doi.org/10.3390/jpm16060328
Primary Topic
Nanoparticle-Based Drug Delivery
Type
article
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article

Nanomedicine in Cardiovascular Inflammation: Novel Diagnostic and Therapeutic Strategies

Efstathios Efstathopoulos, Dimitris Tsiachris, Aikaterini-Eleftheria Karanikola, Agapi Ploussi
Journal of Personalized Medicine
Nanoparticle-Based Drug Delivery
article

Nanomedicine in Cardiovascular Inflammation: Novel Diagnostic and Therapeutic Strategies

Efstathios Efstathopoulos, Dimitris Tsiachris, Aikaterini-Eleftheria Karanikola, Agapi Ploussi
article en

Abstract

Inflammation plays a central role in the pathogenesis and progression of cardiovascular diseases, including atherosclerosis, myocardial infarction and heart failure. Despite advances in conventional diagnostic and therapeutic strategies, limitations in sensitivity, specificity and targeted drug delivery still remain. Nanomedicine has emerged as a promising yet underexplored approach to address these challenges by enabling precise molecular imaging and site-specific therapeutic interventions. This review summarizes current and emerging nanotechnology-based approaches for the diagnosis and treatment of cardiovascular inflammation, highlighting their potential in clinical practice and remaining challenges. In addition, recent advances, including the development of biomimetic nanoplatforms, are discussed, along with future perspectives and the potential integration of artificial intelligence to further enhance precision in cardiovascular medicine.

Journal of Personalized MedicineVol. 16(6)
National and Kapodistrian University of Athens (GR)
Good health and well-being
Openalex Percentile: Top 12%
Nanoparticle-Based Drug Delivery
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