First results of a liver-specific Nope knockout mouse model

Background and objective: Neighbor of Punc E11 (Nope) is a known oncofetal marker in the liver. To understand the function of this membrane protein that is preferentially expressed by epithelial cells, we developed a liver-specific Nope knockout (KO) mouse. Method: We generated the NopeKO mouse [for full text, please go to the a.m. URL]

Authors

Institutions

Publication Details

Journal
German Medical Science (German Research Foundation)
Published
2026-06-18
DOI
https://doi.org/10.3205/26vzmnrw114
Primary Topic
FOXO transcription factor regulation
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

First results of a liver-specific Nope knockout mouse model

D. Nierhoff, E. Könze, S Schmitt, S E Troeder et al.
German Medical Science (German Research Foundation)
FOXO transcription factor regulation
article

First results of a liver-specific Nope knockout mouse model

D. Nierhoff, E. Könze, S Schmitt, S E Troeder, C. Neumann-Haefelin, B. Jakob, B. Zevnik, S. Schulte, S. Zweerink, J.-W. Lackmann
article en

Abstract

Background and objective: Neighbor of Punc E11 (Nope) is a known oncofetal marker in the liver. To understand the function of this membrane protein that is preferentially expressed by epithelial cells, we developed a liver-specific Nope knockout (KO) mouse. Method: We generated the NopeKO mouse [for full text, please go to the a.m. URL]

German Medical Science (German Research Foundation)
University of Cologne (DE), Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases (DE), University Hospital Cologne (DE)
Openalex Percentile: Top 10%
FOXO transcription factor regulation
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.