Fetomaternal hemorrhage: a case highlighting the significance of multifaceted prenatal detection and timely intervention

Introduction Fetomaternal hemorrhage (FMH), a life-threatening obstetric complication with high concealment and poor prognosis, is mostly postnatally diagnosed.Case report This case reports the 30 years old primigravida at 32 + 1 weeks, preoperatively identified with FMH via combined indicators: markedly elevated maternal serum alpha-fetoprotein (AFP) (16698.2 μg/L post-dilution), decreased fetal movement, two non-reassuring fetal heart rate tracings, and polyhydramnios. Emergency cesarean section was done. The neonate had severe anemia (Hb 5.9 g/dL) and metabolic acidosis, with Hb rising to 137 g/dL after 26 mL packed red blood cell transfusion. Maternal K-B test confirmed 1.1% fetal Hb (116 mL blood loss). The neonate was discharged at 40 + 2 weeks corrected gestational age.Conclusion This case emphasizes that the integration of multiple prenatal clinical and laboratory cues facilitates early detection of FMH, thereby contributing to improved perinatal prognosis.

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Publication Details

Journal
The Journal of Maternal-Fetal & Neonatal Medicine
Published
2026-06-18
DOI
https://doi.org/10.1080/14767058.2026.2689204
Primary Topic
Blood groups and transfusion
Type
article
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article

Fetomaternal hemorrhage: a case highlighting the significance of multifaceted prenatal detection and timely intervention

Qinglin Ma, Gao Y, Yuanbin Lu, Guikai Duan
The Journal of Maternal-Fetal & Neonatal Medicine
Blood groups and transfusion
article

Fetomaternal hemorrhage: a case highlighting the significance of multifaceted prenatal detection and timely intervention

Qinglin Ma, Gao Y, Yuanbin Lu, Guikai Duan
article en

Abstract

Introduction Fetomaternal hemorrhage (FMH), a life-threatening obstetric complication with high concealment and poor prognosis, is mostly postnatally diagnosed.Case report This case reports the 30 years old primigravida at 32 + 1 weeks, preoperatively identified with FMH via combined indicators: markedly elevated maternal serum alpha-fetoprotein (AFP) (16698.2 μg/L post-dilution), decreased fetal movement, two non-reassuring fetal heart rate tracings, and polyhydramnios. Emergency cesarean section was done. The neonate had severe anemia (Hb 5.9 g/dL) and metabolic acidosis, with Hb rising to 137 g/dL after 26 mL packed red blood cell transfusion. Maternal K-B test confirmed 1.1% fetal Hb (116 mL blood loss). The neonate was discharged at 40 + 2 weeks corrected gestational age.Conclusion This case emphasizes that the integration of multiple prenatal clinical and laboratory cues facilitates early detection of FMH, thereby contributing to improved perinatal prognosis.

The Journal of Maternal-Fetal & Neonatal MedicineVol. 39(1)
Shenzhen Maternity and Child Healthcare Hospital (CN), Shenzhen Bao'an District People's Hospital (CN)
No poverty
Openalex Percentile: Top 7%
Blood groups and transfusion
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