Multi-cancer detection using a computationally efficient CNN with transfer learning

This study introduces a computationally efficient convolutional neural network (CNN) architecture enhanced with transfer learning for multi-cancer detection using biomedical images. The proposed lightweight CNN model is designed to reduce computational complexity while maintaining high classification performance, making it suitable for deployment in resource-constrained environments. We evaluate this approach on three distinct tumor datasets comprising brain magnetic resonance imaging (MRI) and lung and kidney computed tomography (CT) scans. The model achieves test accuracy of 90.85 ± 2.22%, 98.64 ± 2.43%, and 99.92 ± 0.08% for brain, lung, and kidney cancer classification, respectively, using fivefold stratified cross validation (CV). Transfer learning is employed by pretraining the model on one cancer type and fine-tuning it on the others, requiring only 20 additional epochs to achieve performance comparable to models trained from scratch. The fine-tuning process involves updating the classification part of the CNN and requires approximately 0.014 s per image per epoch using an NVIDIA GeForce GTX 960. Comparative evaluations show that the proposed model outperforms several state-of-the-art pretrained architectures, such as Xception, VGG16, VGG19, MobileNetV2, and DenseNet121. Overall, the model’s effectiveness is evaluated across three types of cancer with distinct morphological characteristics, assessing its performance on both MRI and CT imaging modalities and demonstrating robust performance across diverse tasks and data types. These findings underscore the potential of streamlined deep learning (DL) frameworks in accelerating cancer diagnosis without sacrificing accuracy, especially in settings with limited computational resources.

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Publication Details

Journal
Communications in Statistics - Simulation and Computation
Published
2026-06-18
DOI
https://doi.org/10.1080/03610918.2026.2680237
Primary Topic
Advanced Neural Network Applications
Type
article
Field-Weighted Citation Impact
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article

Multi-cancer detection using a computationally efficient CNN with transfer learning

Dimitrios-Panagiotis Papageorgiou, Vasileios Ε. Papageorgiou, Γεώργιος Πετμεζάς, N Maglaveras et al.
Communications in Statistics - Simulation and Computation
Advanced Neural Network Applications
article

Multi-cancer detection using a computationally efficient CNN with transfer learning

Dimitrios-Panagiotis Papageorgiou, Vasileios Ε. Papageorgiou, Γεώργιος Πετμεζάς, N Maglaveras, Leandros Stefanopoulos
article en

Abstract

This study introduces a computationally efficient convolutional neural network (CNN) architecture enhanced with transfer learning for multi-cancer detection using biomedical images. The proposed lightweight CNN model is designed to reduce computational complexity while maintaining high classification performance, making it suitable for deployment in resource-constrained environments. We evaluate this approach on three distinct tumor datasets comprising brain magnetic resonance imaging (MRI) and lung and kidney computed tomography (CT) scans. The model achieves test accuracy of 90.85 ± 2.22%, 98.64 ± 2.43%, and 99.92 ± 0.08% for brain, lung, and kidney cancer classification, respectively, using fivefold stratified cross validation (CV). Transfer learning is employed by pretraining the model on one cancer type and fine-tuning it on the others, requiring only 20 additional epochs to achieve performance comparable to models trained from scratch. The fine-tuning process involves updating the classification part of the CNN and requires approximately 0.014 s per image per epoch using an NVIDIA GeForce GTX 960. Comparative evaluations show that the proposed model outperforms several state-of-the-art pretrained architectures, such as Xception, VGG16, VGG19, MobileNetV2, and DenseNet121. Overall, the model’s effectiveness is evaluated across three types of cancer with distinct morphological characteristics, assessing its performance on both MRI and CT imaging modalities and demonstrating robust performance across diverse tasks and data types. These findings underscore the potential of streamlined deep learning (DL) frameworks in accelerating cancer diagnosis without sacrificing accuracy, especially in settings with limited computational resources.

Communications in Statistics - Simulation and Computation
National and Kapodistrian University of Athens (GR), Aristotle University of Thessaloniki (GR)
Openalex Percentile: Top 5%
Advanced Neural Network Applications
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