Type IV Takayasu Arteritis Presenting as a Late-Onset Hypertensive Emergency and Transient Ischemia: A Case Report Highlighting Diagnostic Challenges

A 69-year-old female patient presented with a hypertensive emergency and recurrent episodes of left upper extremity paresthesia. While initial cerebrovascular imaging was negative, physical examination revealed a significant blood pressure discrepancy between the upper extremities. Subsequent computed tomography angiography of the abdomen identified abnormal circumferential wall thickening of the infrarenal abdominal aorta extending into the common iliac arteries, consistent with aortitis. Additionally, duplicate left renal arteries were noted, with severe stenosis of the posterior artery driving the hypertensive crisis. These findings supported a diagnosis of Type IV Takayasu arteritis, an exceptional presentation in a patient of advanced age with normal inflammatory markers. The patient was stabilized with intravenous antihypertensive therapy and transferred for multidisciplinary management. This case underscores the importance of considering large-vessel vasculitis in the differential diagnosis of elderly patients presenting with unexplained hypertensive emergencies, as reliance on age demographics or inflammatory markers may delay accurate diagnosis.

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Publication Details

Journal
Cureus
Published
2026-06-19
DOI
https://doi.org/10.7759/cureus.111141
Primary Topic
Vasculitis and related conditions
Type
article
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article

Type IV Takayasu Arteritis Presenting as a Late-Onset Hypertensive Emergency and Transient Ischemia: A Case Report Highlighting Diagnostic Challenges

Diala Al‐Sukhon, Ahmed M Saleh, Zaid El-Ebeisat, Amro Al-Zaben et al.
Cureus
Vasculitis and related conditions
article

Type IV Takayasu Arteritis Presenting as a Late-Onset Hypertensive Emergency and Transient Ischemia: A Case Report Highlighting Diagnostic Challenges

Diala Al‐Sukhon, Ahmed M Saleh, Zaid El-Ebeisat, Amro Al-Zaben, Ibrahim Al-Adayleh
article en

Abstract

A 69-year-old female patient presented with a hypertensive emergency and recurrent episodes of left upper extremity paresthesia. While initial cerebrovascular imaging was negative, physical examination revealed a significant blood pressure discrepancy between the upper extremities. Subsequent computed tomography angiography of the abdomen identified abnormal circumferential wall thickening of the infrarenal abdominal aorta extending into the common iliac arteries, consistent with aortitis. Additionally, duplicate left renal arteries were noted, with severe stenosis of the posterior artery driving the hypertensive crisis. These findings supported a diagnosis of Type IV Takayasu arteritis, an exceptional presentation in a patient of advanced age with normal inflammatory markers. The patient was stabilized with intravenous antihypertensive therapy and transferred for multidisciplinary management. This case underscores the importance of considering large-vessel vasculitis in the differential diagnosis of elderly patients presenting with unexplained hypertensive emergencies, as reliance on age demographics or inflammatory markers may delay accurate diagnosis.

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Vasculitis and related conditions
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