The Anatomical Scaling Law for Degos Disease: A Falsifiable Framework Based on Perforasome Geometry and Node-to-Centroid Alignment

A theoretical framework proposing that Degos lesion morphology is constrained by cutaneous vascular geometry. Computational simulations demonstrate anatomical scaling behavior and motivate a testable perforasome-based model. The paper introduces the Node-to-Centroid Alignment hypothesis as a primary falsification criterion.

Authors

Publication Details

Journal
Zenodo (CERN European Organization for Nuclear Research)
Published
2026-06-18
DOI
https://doi.org/10.5281/zenodo.20741667
Primary Topic
Parvovirus B19 Infection Studies
Type
preprint
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preprint

The Anatomical Scaling Law for Degos Disease: A Falsifiable Framework Based on Perforasome Geometry and Node-to-Centroid Alignment

Thomas S. Mitchell
Zenodo (CERN European Organization for Nuclear Research)
Parvovirus B19 Infection Studies
preprint

The Anatomical Scaling Law for Degos Disease: A Falsifiable Framework Based on Perforasome Geometry and Node-to-Centroid Alignment

Thomas S. Mitchell
preprint en

Abstract

A theoretical framework proposing that Degos lesion morphology is constrained by cutaneous vascular geometry. Computational simulations demonstrate anatomical scaling behavior and motivate a testable perforasome-based model. The paper introduces the Node-to-Centroid Alignment hypothesis as a primary falsification criterion.

Zenodo (CERN European Organization for Nuclear Research)
Peace, Justice and strong institutions
Parvovirus B19 Infection Studies
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