Socioeconomic and clinical determinants of mental health service use: a population-based cohort study exploring frailty as a potential mediator

This population-based cohort study aimed at evaluating the association between clinical and socio-demographic characteristics and recorded access to mental health care. We included over 750,000 adult residents in central Italy, followed from January 2020 to December 2022. Multivariable logistic models were run separately for gender, and for prevalence and incidence of access; the analysis specifically assessed the interaction and the potential modifying role of clinical frailty regarding foreign country of birth and residency in highly deprived areas, through a four-way decomposition framework. A higher prevalence and incidence of mental care access were observed among women, elderly 65+, Italian-born, residents in deprived areas, individuals living alone or with one other person, clinically frail, and Emergency Room frequent users for non-psychiatric diagnosis. The simultaneous presence of clinical frailty and high deprivation resulted in a significant threefold increase in prevalence for female patients (Odds Ratio, OR = 3.02; 95%CI 2.89–3.15). Immigrants have lower access to mental health services, but the interaction between frailty and foreign country of birth reversed the effect (prevalence: OR males = 1.56; 95%CI 1.32–1.84, OR females = 2.39; 95%CI 2.14–2.66; incidence, significant for males only: OR = 1.79; 95%CI 1.42–2.28). The observed confluence of poor health and social vulnerability affecting the recorded access to mental health services suggests the need for integrated health and social care approaches for preventing mental health disorders, while improving equity in the enrollment process.

Authors

Institutions

Publication Details

Journal
Scientific Reports
Published
2026-06-18
DOI
https://doi.org/10.1038/s41598-026-57023-1
Primary Topic
Migration, Health and Trauma
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Socioeconomic and clinical determinants of mental health service use: a population-based cohort study exploring frailty as a potential mediator

Martina Pacifici, Alessio Petrelli, Martina Ventura, Massimiliano Aragona et al.
Scientific Reports
Migration, Health and Trauma
article

Socioeconomic and clinical determinants of mental health service use: a population-based cohort study exploring frailty as a potential mediator

Martina Pacifici, Alessio Petrelli, Martina Ventura, Massimiliano Aragona, Valeria Fano, Anteo Di Napoli, Fabio Voller, Roberta Ciampichini, Alberto Zucchi, Claudio Rosini
article en

Abstract

This population-based cohort study aimed at evaluating the association between clinical and socio-demographic characteristics and recorded access to mental health care. We included over 750,000 adult residents in central Italy, followed from January 2020 to December 2022. Multivariable logistic models were run separately for gender, and for prevalence and incidence of access; the analysis specifically assessed the interaction and the potential modifying role of clinical frailty regarding foreign country of birth and residency in highly deprived areas, through a four-way decomposition framework. A higher prevalence and incidence of mental care access were observed among women, elderly 65+, Italian-born, residents in deprived areas, individuals living alone or with one other person, clinically frail, and Emergency Room frequent users for non-psychiatric diagnosis. The simultaneous presence of clinical frailty and high deprivation resulted in a significant threefold increase in prevalence for female patients (Odds Ratio, OR = 3.02; 95%CI 2.89–3.15). Immigrants have lower access to mental health services, but the interaction between frailty and foreign country of birth reversed the effect (prevalence: OR males = 1.56; 95%CI 1.32–1.84, OR females = 2.39; 95%CI 2.14–2.66; incidence, significant for males only: OR = 1.79; 95%CI 1.42–2.28). The observed confluence of poor health and social vulnerability affecting the recorded access to mental health services suggests the need for integrated health and social care approaches for preventing mental health disorders, while improving equity in the enrollment process.

Scientific Reports
Agenzia Regionale per la Protezione Ambientale del Piemonte (IT), Regional Health (US), Health Protection Agency (MV), San Gallicano Hospital (IT)
No poverty
Openalex Percentile: Top 5%
Migration, Health and Trauma
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.