Stroke Severity and Functional Benefit of Thrombectomy in Acute M2 Middle Cerebral Artery Occlusion
Recent randomized trials reported no overall functional benefit of endovascular treatment (EVT) for distal medium-vessel occlusion (DMVO) and did not identify consistent effect modifiers to guide patient selection. Consequently, the role of EVT—particularly for M2 occlusions—remains controversial. We investigated whether baseline clinical severity modifies the association between successful recanalization and 90-day outcome in patients with M2 occlusion.
Authors
- Maarten G. Lansberg (ORCID: https://orcid.org/0000-0002-3545-6927)
- Jeremy Josef Heit (ORCID: https://orcid.org/0000-0003-1055-8000)
- André Kemmling (ORCID: https://orcid.org/0000-0001-8930-1894)
- Tobias Djamsched Faizy (ORCID: https://orcid.org/0000-0002-1631-2020)
- Christian Heitkamp (ORCID: https://orcid.org/0000-0002-8988-0918)
- Helge C. Kniep (ORCID: https://orcid.org/0000-0001-5258-2370)
- Gregory W. Albers (ORCID: https://orcid.org/0000-0003-0263-4632)
- Hermann Krähling (ORCID: https://orcid.org/0000-0003-2639-8400)
- Lukas Meyer (ORCID: https://orcid.org/0000-0002-3776-638X)
- Karsten Alfke (ORCID: https://orcid.org/0009-0001-4223-6404)
- Gabriel Broocks (ORCID: https://orcid.org/0000-0002-7575-9850)
- Jens Fiehler (ORCID: https://orcid.org/0000-0001-8533-7478)
- Paul Stracke
- Vivek Srikar Yedavalli (ORCID: https://orcid.org/0000-0002-2450-4014)
- Jens Minnerup (ORCID: https://orcid.org/0000-0002-0382-5759)
- Emily Hoffmann
Institutions
- Johns Hopkins University (US)
- Universität Hamburg (DE)
- Philipps University of Marburg (DE)
- Johns Hopkins Medicine (US)
- MSH Medical School Hamburg – University of Applied Sciences and Medical University (DE)
- Helios Hospital Schwerin (DE)
- University Hospital Münster (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- University Hospital Schleswig-Holstein (DE)
- Neurological Surgery (US)
- University of Lübeck (DE)
- Stanford University (US)
Publication Details
- Journal
- Neurology
- Published
- 2026-06-18
- DOI
- https://doi.org/10.1212/wnl.0000000000218179
- Citations
- 1
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 12.10