Two new ester glycosides from <i>Portulaca oleracea</i> L. and their bioactivities

Two new ester glycosides named oleracrylate A (1), and oleracrylate B (2) were isolated from Portulaca oleracea L. The structures of the two compounds were verified by 1D, 2D NMR and UHPLC-ESI-QTOF/MS methods. Furthermore, the anti-inflammatory activities of the two ester glycosides from P. oleracea were studied. The results indicated that the two compounds could suppress the production levels of IL-1β and TNF-α in RAW 264.7 cells above 10 μM, served as potential anti-inflammatory agents, and enriched the chemical diversity of P. oleracea.

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Publication Details

Journal
Natural Product Research
Published
2026-06-17
DOI
https://doi.org/10.1080/14786419.2026.2683705
Primary Topic
Antioxidants, Aging, Portulaca oleracea
Type
article
Field-Weighted Citation Impact
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article

Two new ester glycosides from Portulaca oleracea L. and their bioactivities

Pengyan Liu, Xixiang Ying, Jing Liu, Shengnan Guo et al.
Natural Product Research
Antioxidants, Aging, Portulaca oleracea
article

Two new ester glycosides from Portulaca oleracea L. and their bioactivities

Pengyan Liu, Xixiang Ying, Jing Liu, Shengnan Guo, Zheming Ying, Zhiwei Zhang, Xiyue Gao
article en

Abstract

Two new ester glycosides named oleracrylate A (1), and oleracrylate B (2) were isolated from Portulaca oleracea L. The structures of the two compounds were verified by 1D, 2D NMR and UHPLC-ESI-QTOF/MS methods. Furthermore, the anti-inflammatory activities of the two ester glycosides from P. oleracea were studied. The results indicated that the two compounds could suppress the production levels of IL-1β and TNF-α in RAW 264.7 cells above 10 μM, served as potential anti-inflammatory agents, and enriched the chemical diversity of P. oleracea.

Natural Product Research
Dalian Medical University (CN), Liaoning University of Traditional Chinese Medicine (CN), First Affiliated Hospital of Dalian Medical University (CN)
Openalex Percentile: Top 10%
Antioxidants, Aging, Portulaca oleracea
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