Comparative visual outcomes of inverted ILM flap “covering” versus “stuffed” techniques for macular hole surgery

PURPOSE: To compare the functional and anatomical outcomes of the inverted internal limiting membrane (ILM) flap covering and stuffed techniques in primary macular hole (MH) surgery. METHODS: This retrospective case series included 57 eyes that underwent inverted ILM flap surgery by a single surgeon (covering, n = 33; stuffed, n = 24). Best-corrected visual acuity (BCVA) and optical coherence tomography findings, including restoration of the external limiting membrane (ELM) and ellipsoid zone (EZ), were assessed preoperatively and at 1 and 6 months postoperatively. RESULTS: There were no significant differences in preoperative characteristics or MH closure rates between groups. BCVA improved significantly in both groups postoperatively; however, BCVA was significantly better in the covering group at 1 month (P = 0.005) and 6 months (P = 0.001). Restoration of the ELM and EZ was more frequent in the covering group at 1 month (ELM, P < 0.001; EZ, P = 0.002) and 6 months (ELM, P < 0.001; EZ, P = 0.001). CONCLUSION: Although both techniques achieved comparable anatomical closure, the covering method provided superior visual and outer retinal recovery for a wide range of macular holes, including medium-to-large cases. These findings suggest that the covering technique may be preferable as a standard approach for primary MH surgery.

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Publication Details

Journal
Graefe s Archive for Clinical and Experimental Ophthalmology
Published
2026-06-18
DOI
https://doi.org/10.1007/s00417-026-07329-7
Primary Topic
Retinal and Macular Surgery
Type
article
Field-Weighted Citation Impact
0.00

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article

Comparative visual outcomes of inverted ILM flap “covering” versus “stuffed” techniques for macular hole surgery

Toru Nakazawa, Hiroshi Kunikata, Naoko Aizawa
Graefe s Archive for Clinical and Experimental Ophthalmology
Retinal and Macular Surgery
article

Comparative visual outcomes of inverted ILM flap “covering” versus “stuffed” techniques for macular hole surgery

Toru Nakazawa, Hiroshi Kunikata, Naoko Aizawa
article en

Abstract

PURPOSE: To compare the functional and anatomical outcomes of the inverted internal limiting membrane (ILM) flap covering and stuffed techniques in primary macular hole (MH) surgery. METHODS: This retrospective case series included 57 eyes that underwent inverted ILM flap surgery by a single surgeon (covering, n = 33; stuffed, n = 24). Best-corrected visual acuity (BCVA) and optical coherence tomography findings, including restoration of the external limiting membrane (ELM) and ellipsoid zone (EZ), were assessed preoperatively and at 1 and 6 months postoperatively. RESULTS: There were no significant differences in preoperative characteristics or MH closure rates between groups. BCVA improved significantly in both groups postoperatively; however, BCVA was significantly better in the covering group at 1 month (P = 0.005) and 6 months (P = 0.001). Restoration of the ELM and EZ was more frequent in the covering group at 1 month (ELM, P < 0.001; EZ, P = 0.002) and 6 months (ELM, P < 0.001; EZ, P = 0.001). CONCLUSION: Although both techniques achieved comparable anatomical closure, the covering method provided superior visual and outer retinal recovery for a wide range of macular holes, including medium-to-large cases. These findings suggest that the covering technique may be preferable as a standard approach for primary MH surgery.

Graefe s Archive for Clinical and Experimental Ophthalmology
Tohoku University (JP)
Japan Science and Technology Corporation, Japan Society for the Promotion of Science
Openalex Percentile: Top 7%
Retinal and Macular Surgery
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Comparative visual outcomes of inverted ILM flap “covering” versus “stuffed” techniques for macular hole surgery — Toru Nakazawa, Hiroshi Kunikata, et al. · Graefe s Archive for Clinical and Experimental Ophthalmology (2026) | TGRS Research Map | TGRS